Tags for this video have been changed from 'nutritional, supplement, magic, pill, weight, loss, senate, hearing, FDA, june 22' to 'nutritional supplement, magic pill, weight loss, senate hearing, FDA, june 22' - edited by xxovercastxx

um
As mentioned, diabetes mellitus type 1 is genetic, you need regular insulin injections because, without it your blood sugar levels will be sky high, and sugar in the blood leads to glycation. Glycation is where sugars attach to proteins (such as the ones in your red blood cells) and then become useless/damaging. The amount of glycation is measured by a test called the HbA1C, something diabetics will be familiar with. Glycation cannot be avoided by faith...

The comment @Sniper007 made about curing diabetes is almost true however, as it has been demonstrated time and time again (in studies for over 20 years) that calorie restricted diets (and to a lesser extent weight loss) can basically cure diabetes (type 2). It is thought that one of the main reasons for this is that it helps to reduce adipose tissue (fat) that has been laid down in places like the pancreas and liver. A small reduction in the adipose tissue in the pancreas helps it regain much of its lost function. This calorie restriction doesn't appear to work in all type 2 diabetics, but it does work in many.

Info about the adipose tissue deposition/pancreas issue.
dvr.sagepub.com/content/early/2012/09/10/1479164112455817.full.pdf+html
http://www.endocrine-abstracts.org/ea/0015/ea0015s39.htm

What an idiotic statement about diabetes. There's much higher rates of diabetes type two in families with diabetes than type 1. So there are people who are more predisposed to it independently of lifestyle/body weight. In some people, where increased body weigh and sedentary life style are the main risk factor then it has been shown that gastric bypass sugary can 'cure it' independently of weight loss with the current thinking being that hormones released by the stomach in contact with food can have a massive effect on our endocrine system as well as satiety.
Regardless, the argument is stupid - if you found out that you had a enzyme deficiency at causes a stroke later on in life and the treatment/rehab would cost you millions of pounds. The 'i exercised and dieted' view doesn't help pay the cheque for something that was set in stone when your mum and dad had an accident all those years ago.

uhm. 1:21 is DE-motivation if you ask me.

Yeah, I agree with eric. Muscles and weight loss = yay, but there are limits. As with everything else, it's moderation.

Recently started a weight lifting program myself and yes, I've definitely benefited from it, but yeah, I also just don't see the appeal of the 'roided out look.

*ban

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@VoodooV @rottenseed @braindonut

I'm definitely not a doctor and I'm probably not saying anything you haven't heard before, but; if you're getting acid reflux often, a bit of a diet change and some weight loss could do wonders. This is purely from my own experience of developing a near reliance on antacids for get through the day and night; to then eating less and losing 45 lbs.; to not having had an antacid for several months now.

Obviously I have no idea of your fitness levels, but I don't think it's too crass to assume that a lot of the people here on Videosift are probably in the same likes-to-sit-a-lot crowd that I'm part of.

lul. dum, but i like attention


>> ^bmacs27:

I suggest you read more books. You have an aforementioned idiocy issue that I think you need to work on. I apologize if my suggestion of positive lifestyle choices was unsolicited. I know it can be hard to grapple with idiocy, but we are in the midst of an idiocy epidemic, so I'd appreciate it if you wouldn't contribute to further idiocy by voicing your opinions.
Congratulations on your weight loss.
>> ^CaptainPlanet:
also, please nobody assault anyone for suggesting positive lifestyle choices, Even if those suggestions are unsolicited.

I suggest you read more books. You have an aforementioned idiocy issue that I think you need to work on. I apologize if my suggestion of positive lifestyle choices was unsolicited. I know it can be hard to grapple with idiocy, but we are in the midst of an idiocy epidemic, so I'd appreciate it if you wouldn't contribute to further idiocy by voicing your opinions.

Congratulations on your weight loss.
>> ^CaptainPlanet:

also, please nobody assault anyone for suggesting positive lifestyle choices, Even if those suggestions are unsolicited.

My claim is that there is insufficient data to show a causal link between being significantly overweight (within reason, say BMI < 40) and negative health consequences when controlling for other known detrimental behaviors and health risk factors. That said, there is certainly an interaction effect whereas a higher BMI can tend to exacerbate underlying health issues/comorbidities. That is, it is erroneous to look at a fat person and tell them that they are necessarily unhealthy without having a more nuanced understanding of their overall health, other risk factors and activity levels.

Further, I believe it is erroneous to claim that long term weight loss is an achievable goal in all individuals, and that instead encouragement should be directed towards improvement in the overall health of the individual rather than emphasizing the primary goal of weight loss. Even if it were clear beyond all doubt that obesity directly caused the negative health effects it is psychologically pragmatic to avoid conflating body-image issues and health concerns. Finally, from an etiquette standpoint, it is inappropriate and counterproductive to comment on the health consequences of the behavior of an individual unless you are employed by that individual as a health professional or are otherwise a close, concerned acquaintance of that individual.

In other words saying, "you fatties shouldn't be on TV, think of the children," isn't exactly productive nor appropriate.

Clear enough?

Cheers. At least you are attempting some objectivity.

>> ^scannex:

Direct question then.
Is it your stance that claiming there are negative health consequences from being obese is erroneous?
Is it your stance that there is insufficent data to show a causal link between being significantly overweight (obese) and health problems?
>> ^bmacs27:
@scannex The claim is that many of the negative health consequences associated with obesity, e.g. cardiac arrest, are in fact dependent on other factors with which obesity is commonly comorbid. I showed you a case in which less hypertensive adult women showed no effect of BMI on mortality across the board. Your studies failed to address that so far. Even in the latest, it shows that many of the complications involve comorbidity, not obesity in its own right. Even when it talks about diabetes it talks about the protective effect of vitamin E. Now, if you want to start talking about joint replacements or whatever, fine, but then we should probably tell people to be careful about their morning run too.

I'm typically not one for anecdotal evidence myself, but I don't need to rely on it. There is very little data on successful techniques for long term weight loss. Here's an example. Now, not everyone will interpret these results in the same way that I do. On my reading, people that maintained weight loss needed to check their weight, reduce their fat intake, and expend more energy than people that are naturally weight stable at that weight. In fact, people that lost weight, and regained it had effectively the same habits as people that are weight stable at the lower weight. In other words, weight stable fat people and weight stable thin people exercise and eat the same amounts. Granted, there were some that were able to maintain this increased activity level and highly restrictive diet, however I would suspect if you were to investigate that group you would likely find a higher incidence of psychological issues surrounding body-image, and likely an increased incidence of OCD. Now if your claim is true, the people that lost weight down to an average of 167 pounds or so (the average weight of the weight stable controls), should have been able to have equivalent habits to those controls and maintain that weight as their BMR should be equivalent. Clearly the data shows your claim to be false. They need to maintain an increased activity level and lower fat intake in order to maintain the same weight.

>> ^Duncan:

@bmacs27 You're using every cliche in the book. Basal Metabolic Rates vary in negligible amounts between people of the same gender, age, height, and weight. If your body doesn't get the energy it needs from an outside source, it will break down itself for fuel. And your anecdotal evidence means very little. Argue all you want about how body fat has little to do with health, but don't go saying some people can't lose it (genetic conditions notwithstanding).

>> ^bmacs27:

@scannex Dude... are you really citing a marketing campaign for weight loss pushers? I bet you I could find data that shows the effectiveness of penis enhancement pills too. If you took a few you might find you like 'em thick ;-). Try some primary literature, and I'll respond in kind.

Try to refute this claim: "Overweight or mildly obese individuals with otherwise normal bio-markers show no decrease in life expectancy from normal."

If you can't, then tell me why it is okay to berate someone about their weight knowing nothing about their health overall?


I don't what source your quote came from.
But I will happily refute it.
Here you go, from the NIH
A referenced article from Oxford
Another study
Heres the wiki for Leptin so you can understand why the release of leptin (from having too much fat) creates a vicious cycle causing you to eat more and more.
Another article on the increased risk for diabetes in the obese from you know... the journal NATURE

This is not a "jury is out" scenario. Directly and indirectly obesity causes a myriad of health complications and increased risk for debilitating and deadly diseases.

You are fighting against countless areas of research with one obscure data point from what is probably a single study that I have no source for. Even with the source its an incredibly uphill battle for you.

Being Obese is unhealthy, and except for in an EXTREME minority of genetic cases, completely modifiable.

@Duncan And yet this is the commonly suggested course of action for those overweight. Eat 1000-1200 calories a day, and exercise. That's a recipe for disaster. Further, your claim that if you intake fewer calories than you expend you will lose weight. This is not necessarily true. Your body is not a bunsen burner. That's why we have terms like "metabolism" as in so and so has a high metabolism or a low metabolism. In other words, some people can eat and eat and eat, and their body will simply convert the excess energy into heat. For others, that energy is stored as fat. My claim is that there are people for whom prolonged caloric restriction will not result in continued weight loss. Instead the body will continue to store the energy it receives as fat and your brain will be deprived of the energy it needs to allow activity levels necessary to burn anything off. Even with continued restriction. There are cases (e.g. with OCD patients) that prolonged weight loss can be achieved, but often it's simply impossible.

With regards to "life-style change," I agree. It's necessary. However, losing weight isn't. Much more success has been reported encouraging an active lifestyle. Eat until you are sated. That's okay (assuming you don't have a broken sensory system in that regard). People that pursue this approach will usually not lose weight, but they will become healthy. All of their bio-markers (e.g. cholesterol) often come into check. They are active, happy, and healthy. Yet still, people would somehow feel justified sending them a letter telling fatty to get off their ass.

I'll give an example. I watched my girl eat 1200 calories a day for six months. She's 5'2" at 180. The first month of this brought her down to 165/170, but the following five brought her no further. I watched her. She measured every meal with a measuring cup. She's also a geneticist, so she knows a thing or two about the relevant biochem. She was depressed as hell, and her activity level dropped. She was miserable and didn't even really lose substantial weight.

Now, she bikes at least 10-12 hilly miles a day, swims a couple miles three times a week, and does yoga. She eats when she's hungry and stops when she's full. She eats healthily for the most part, but rewards herself with a sweet now and again. Every measure known to correlate with health shows that she is healthy despite her weight. People call her fat all the time. There's just no need. Her doctor doesn't, because many doctors these days know BMI is a bullshit measure. She's not a weird case. I mentioned by buddy the pullup champ in a previous post. The dude was vegetarian in boot camp. He doesn't have an ounce of fat on him, and can do effectively perpetual pushups. He's technically "obese." For a medical term, it's about as useful as "idiot."

The fact is evidence is mounting that your disposition towards retaining fat probably has more to do with what was eaten by your mother during pregnancy than anything you do in your lifetime (other than maybe early childhood). Your body has a weight it would like to keep, and it will succeed in keeping it. If people would just change the societal pressure towards becoming healthy rather than losing weight people doomed to carry extra pounds wouldn't have to feel like outcasts, and would probably be more likely to pursue the correct goal. Instead, most people here seem to think it's okay to berate strangers about their weight. Let them talk to their doctor. If their doctor is good with it, you probably should be too.

@scannex Dude... are you really citing a marketing campaign for weight loss pushers? I bet you I could find data that shows the effectiveness of penis enhancement pills too. If you took a few you might find you like 'em thick ;-). Try some primary literature, and I'll respond in kind.

Try to refute this claim: "Overweight or mildly obese individuals with otherwise normal bio-markers show no decrease in life expectancy from normal."

If you can't, then tell me why it is okay to berate someone about their weight knowing nothing about their health overall?

>> ^bmacs27:

Every study I've seen shows that diets of that sort yield short term weight loss although subjects generally reacquire the weight within a year of stopping the diet, and report depression during the diet. Prove me wrong.


Ok...
Weight Watchers Success Stories
People failing to maintain their diets and permanently alter their eating and exercise behavior after a successful diet is behavioral.
Failing at anything can cause depression. This is not a complex phenomenon. Cessation of an activity you previously relied on for happiness is bound to make you less happy (biochemically if nothing else), and like quitting smoking will always be a difficult temptation.

You keep using the word diet as something you can just go on and off of. That's the problem; 'Going on a diet' implies that it's temporary. What's needed to eat and live healthy is a permanent lifetstyle change. In other words, you don't stop the diet. The previous diet is what led to getting overweight in the first place, so of course they gain the weight back if they start eating like that again. Exercise all you want, if you take in more calories than you expend, you will gain weight. If you expend more calories than you take in, you will lose weight. It doesn't matter if you have a problem with that, or if people get depressed, or if you just straight up don't think it's a health issue (it is), that's how it works. That's why this argument takes place when this issue is brought up. It really is just a matter of will power and education on nutrition. How much will power's needed depends on the person, along with their knowledge on nutrition and eating well. Breaking these long standing habits can be incredibly tough, but not impossible.

There's a lot of grey area in the discussion of being overweight and healthy/fit/etc. If you have terrible eating habits, exercise will only make things a bit better; it wont magically counteract all the negative aspects of your body composition, or of the food you eat. The effect food can have on a person astronomically outweighs the potential effects of exercise. That's in no way saying exercise is pointless, but if you're diet's not in check, the exercise alone is like ordering a diet coke with your ten cheeseburgers.
>> ^bmacs27:

You guys aren't listening to what I'm saying. There is nothing wrong with eating right and exercising. I have a problem with caloric restriction, or as it is commonly called "dieting." Further, I have a problem with judging health from weight or BMI. There is very little data to back that up, and in fact the data suggest that a low BMI is actually more problematic than a moderately high 30ish BMI in terms of life expectancy. My issue is that it's been so ingrained in people to associate weight loss (an aesthetic issue) with fitness (a health issue). There are plenty of people that are fit, and no matter what they do, will carry extra weight.
To me "eating right" means eating healthy foods, e.g. whole foods, fruits, vegetables, proteins as your primary nutrition rather than fatty and heavily sweetened foods. Exercise is the most important part of the equation. The data shows that so long as you are not sedentary you can pretty much eat and weigh whatever with little to no health consequence.
The depression does not come simply from the lack of eating, and thus the cessation of a rewarding activity. It comes from the diversion of energy away from active use (e.g. in the nervous system) and towards the restocking of fat stores. In other words, you'll never lose weight, and instead will just be bummed out all the time.
You talk of "millions of people" that have successfully lost weight. I'd like to see a data that shows a diet emphasizing caloric restriction leading to long term reductions in weight. Every study I've seen shows that diets of that sort yield short term weight loss although subjects generally reacquire the weight within a year of stopping the diet, and report depression during the diet. Prove me wrong.

You guys aren't listening to what I'm saying. There is nothing wrong with eating right and exercising. I have a problem with caloric restriction, or as it is commonly called "dieting." Further, I have a problem with judging health from weight or BMI. There is very little data to back that up, and in fact the data suggest that a low BMI is actually more problematic than a moderately high 30ish BMI in terms of life expectancy. My issue is that it's been so ingrained in people to associate weight loss (an aesthetic issue) with fitness (a health issue). There are plenty of people that are fit, and no matter what they do, will carry extra weight.

To me "eating right" means eating healthy foods, e.g. whole foods, fruits, vegetables, proteins as your primary nutrition rather than fatty and heavily sweetened foods. Exercise is the most important part of the equation. The data shows that so long as you are not sedentary you can pretty much eat and weigh whatever with little to no health consequence.

The depression does not come simply from the lack of eating, and thus the cessation of a rewarding activity. It comes from the diversion of energy away from active use (e.g. in the nervous system) and towards the restocking of fat stores. In other words, you'll never lose weight, and instead will just be bummed out all the time.

You talk of "millions of people" that have successfully lost weight. I'd like to see a data that shows a diet emphasizing caloric restriction leading to long term reductions in weight. Every study I've seen shows that diets of that sort yield short term weight loss although subjects generally reacquire the weight within a year of stopping the diet, and report depression during the diet. Prove me wrong.