scannex

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Comments to scannex

siftbot says...

Happy anniversary! Today marks year number 10 since you first became a Sifter and the community is better for having you. Thanks for your contributions!


siftbot says...

Happy belated anniversary! Due to a glitch in the Matrix, we forgot to mark year number 2 since you first became a Sifter. The community wouldn\'t be the same without you. Thanks for your contributions!


bmacs27 says...

I know that there are studies regarding adult weight in the mice, and my understanding (assumption) is that the mice were raised away from the mothers. This data is mostly coming second hand from my gf, so I'll see if I can track down the source. Also, it had been a year or so since she had looked closely at it. The human data is difficult to interpret because you are typically talking about isolated populations that may not be representative. Still, this stuff is crazy in that it opens the door to non-Mendellian, almost even Lamarckian inheritance. We just don't know enough about genetics to say anything definitive about mechanism imho. I think in biology people often don't take seriously enough the possibility of latent common cause when explaining correlations. In such complex dynamical systems it seems like a near certainty that we're missing something.

Re google scholar: I'm pretty sure it crawls pub med. Pub med doesn't work for me in because it often misses many of the stats/cs/engineering/mathematical journals I need for my modeling work.

bmacs27 says...

I appreciate your tone. I really do. I just wanted to leave you with some suggested google scholar searches. If you haven't already, check out the recent research in gametic or transgenerational epigenetic inheritance. It'll be really jargony and difficult to understand. One take home is that the gametic accessibility of genetic material for transcription has been shown to have reliable effects on the phenotype of progeny in animal models. Further, human studies have shown transgenerational effects on the adult weight of offspring in response to the diet of the mother during pregnancy and even in response starvation events dating back further generations (although the mechanism is not necessarily known).

Anyway, nice chat.

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