lose \ˈlüz\
Verb: Be deprived of or cease to have or retain (something): "I've lost my appetite". Cause (someone) to fail to gain or retain (something): "you lost me my appointment at the university".

loose \ˈlüs\
Adjective: Not firmly or tightly fixed in place; detached or able to be detached: "a loose tooth".
Verb: Set free; release: "the hounds have been loosed".

loser \ˈlü-zər\
Noun: A person or thing that loses or has lost something, esp. a game or contest. A person who accepts defeat with good or bad grace, as specified: "they should concede that and be good losers"

looser \ˈlüs-ər\
Adjective: Not firmly or tightly fixed in place; detached or able to be detached: "a loose tooth". Not held or tied together; not packaged or placed in a container: "wear your hair loose".