@jwray are you saying that US citizens are genetically the most violent in the world?

Aren't must asians lactose intolerant, as their ancient ancestors never drank milk on a regular basis? Interestingly it was evolution that gave neolithic european and middle eastern peoples the ability to digest and process lactose as adults, a genetic mutation that soon became widespread.

But for asia, must be a difficult market to break into.

Yeah, you don't have to die, just ruin your chances to pass on your (faulty) genetic code.

" The prime tenet of the Darwin Awards is that we are celebrating the self-removal of incompetent genetic material from the human race. Therefore, the potential winner must be deceased, or at least incapable of reproducing. The traditional method is death. However, an occasional rebel opts for sterilization, which allows her more time to enjoy the dubious notoriety of winning a Darwin Award. " - Darwin Awards, rules.

I cried. Idk if I ever said anything here, but I've been only on occasionally because I had a daughter born with a rare genetic disorder that my wife and I both carried recessively.

It's called NPC which is an acronym for Niemann-Pick Disease Type C (it also makes it annoyingly difficult to search for because I get all kinds of results about non player characters).
http://nnpdf.org/overview/#NPC

The disease itself is fairly horrifying. That sounds like strong language, but click on this link to see the progression of the disease if you too want to cry: http://nnpdf.org/the-disease/the-progression-of-niemann-pick-disease/

Fortunately, we're part of an experiment that is treating people with a very promising success rate for halting the progression of symptoms.

*promote

I think this narration makes a lot of assumptions.

That wolf was never domesticated. Domestication is a genetic adaptation that involves retaining juvenile traits that allow an animal to overcome the boundary that would instinctively cause them to flee or fight. This would take many generations. You can imagine how that adaptation would be advantageous to animals that benefit from living at the edges of human settlement.

There's no way to know why that wolf interacted the way it did but it was wild and posed a potential risk due to it's instinctive programming.

Happy that it remained an uplifting story. But it's not responsible to spread the narrative that you can domesticate a wild animal.

I tend to view the stigmatisation of a word to this degree as counter-productive since it shifts the focus away from the real problem - i.e. chronic inequality of income between black and white communities through poor public services that feeds a lack of opportunity for income mobility. Time spent discussing the degree to which users of the word should be shunned, whether it's said by a comedian, other black people, actual racists, is time not being spent discussing those material issues.

The base case of racism, i.e. the perpetuation of the view that black people are somehow genetically inferior or deserve to be subjugated in rights still certainly exists. What I suspect is more prevalent nowadays is discrimination founded in economic inequalities - the view that because black people are more likely to be poor, making the reflexive assumption they are more likely to resort to crime, and therefore are more dangerous and should be implicitly subject to harsher penalties. Which comes back to my main point, the best way to fix that is to actually narrow those economic inequalities.

Club Penguin has mapped your genetic sequence and is producing clones of you that are fully hacking your identity. CAPTCHA needs to be updated in order to differentiate between you and the infinite number of clones of you.

Thing that really sticks in my throat here.

The most generous current estimate of trans % by population is 0.6%.

The mother of the child here is a vehement and very pro-active trans rights campaigner.

I don't know the proportion of life long trans campaigners, but I'm pretty sure the odds of them having a trans kid are vanishingly small. Much more so for such an extreme and unusual case as this one.

We are both relegated to pure speculation here but, I know at least one example (my brothers partner) of a girl being raised by a lesbian mother, who had deep emotional problems instilled into her from a very early age. i.e. men are bad, she should be attracted to women etc.

Took her well into adulthood to get over that and she is still a mixed up person (mother is to put it politely; a bit mental)

This is a different example of course, but the underlying problem and how it messed her up for most of her childhood seems like it could be similar. We are so used to the prejudices against "normal" gender roles and sexual orientation that it is perhaps easy to forget that this can work just as easily in reverse.
The problem can essentially be asshole parents instilling a mixed up and narrow concept of what is normal. Which either restricts their existing exploration of identity, or actively coerces towards a particular outcome.

IDK, you may just be right and the kid manifested this underlying genetic problem at a very early age. Her mother may be a perfectly even handed and caring person etc. etc.

It just concerns me that it could so easily be the other way around. But you are right about many people simply adopting alternative gender roles rather than physically transitioning. But if this kid starts the hormone blockers, she is sterile for life and will undergo irreversible changes in her development.

If she were to change her mind later in life as she matures... that 40% suicide rate is no joke

& yeh there are certainly strong arguments from inside the trans community against ideas of non binary genders. Most trans people are one gender wishing to transition to, or be treated as the other gender.

I can see an argument for perhaps having a third intermediary gender, beyond that it seems more like lifestyle choices than actual gender issues. e.g. like you say a T.V. man who likes to dress as a woman isn't someone who wants to be a woman, or even gay. It's just a man who likes to feel beautiful in a dress and makeup (to quote Eddie Izzard "male lesbian").

Anyway I don't think you have said anything offensive. This is a mire of a subject and anyone reasonable is going to appreciate your (our) confusion & concerns.

You're kidding, right?
Do I have to make a list? On every continent white people visited (if you can call showing up and not really leaving a visit) we fucked up the lives of a good portion of the people living there.
Sure, mankind has always been cruel, in every corner of the earth. However, white people are to murder, theft and slavery what Coca Cola is to refreshing diabeeetus (yes, that's how it's spelled). A fucking international enterprise whose traces can be found everywhere. On every fucking continent.
I hope we can agree on that. Otherwise, here's a short list: Gippsland Massacres, Nagasaki, Opium Wars, My Lai Massacre, fucking Iraq, Crusades, Apartheid, Herero and Namaqua genocide, that whole Columbus mess, Trail Of Tears and transatlantic slave trade (because why the fuck not?). Oh, my bad, I forgot the freaking Holocaust and starting 2 World Wars.
Who does this? Who? White people, that's who. Europeans and their descendants.
Would you like to argue that level of evil is genetic? I won't.
It's cultural. We europeans (and later our emigrated offspring) always thought we're better than everybody else, we had god on our side (and the Pope agreed!). Probably a leftover from the Roman Empire. And that's why everywhere we go, we steal, murder or occupy the shit out of every place. No other collection of ethnic groups has so much blood on their hands and it's not because we're worse DNA constructs than the others. All humans are capable of evil, it just takes a certain way of thinking to go that far.
Thankfully, we wrecked our own continent so badly during WW2, that we finally started to improve our ways. But here's the problem: we just started. We're far from being done.
Orban, LePen, Farage, Putin, Petry and last but not least Trump.

CRISPR-Cas9
Bring me a gene
Encoding for a specific protein
Make a few snips at this coded locus
You work so well inside a streptococcus
Cas9
I'm so alone
Without your scissors in my chromosome
Cut me up and do it clean
CRISPR-Cas9 bring me a gene

CRISPR-Cas9
Keep me a gene
A viral sequence you've already seen
Chopped into bits and stored as genomic
With clustered repeats
That are palindromic
Cas9
Bind with this code
Use it to target infections of old
Immunized like a vaccine
CRISPR-Cas9 keep me a gene

CRISPR-Cas9
Cut me a gene
With a precision that I've never seen
Unzip a strand and interrogate it
Seek out your sequence until you locate it
Cas9
Lock into place
And do your job as endonuclease
Chop just like a guillotine
CRISPR-Cas9 cut me a gene

Snip snap!
CRISPR-Cas9
CRISPR-Cas9

CRISPR-Cas9
Bring me a gene
By commandeering my repair routine
A strand to match your severed location
For some homologous recombination
Cas9
Cheap and precise
Rewriting genomes from microbes to mice
And soon the humble human being
CRISPR-Cas9 bring me a gene

CRISPR-Cas9
Give us a gene
Give us a miracle like that one Nazarene
‘Cause giving the lame their legs and the blind their sight is
In view for dystrophy and retinitis
But CRISPR-Cas9
What if you fall
Outside our power and inside us all
That really could incite a scene

When this terrible wonderful power unsettling
Opens the door to unethically meddle
Is ev’ry congenital malady bettered
Sufficient to warrant genetics unfettered
To modify man in the manner of Gattaca
Raise up a mammoth or make a rattata
Dramatical medical means to eradicate aging
Or cancer or make a fanatic
A mass epidemic a weapon nefarious
Single mosquito to wipe out malaria
Send in a viral infection to ferry a
Cure to the cells of an HIV carrier
Freed of disease as we're free to uncover
What nature and accident failed to discover
And free to be other than
All that we ever have been

CRISPR-Cas9
CRISPR-Cas9

Oh CRISPR-Cas9
Bring us a gene
You wondrous ribonucleoprotein
You have the power to vanquish or save us
Who would have thought that the microbe that gave us
Cas9
S. pyogenes
The source of strep and flesh-eating disease
Housed this marvellous machine
Full of uses great and obscene
CRISPR-Cas9 bring us
Please don't sting us
Cas9 bring us a gene

With adenine
And thiamine
Incite a scene
Cas9 bring us a gene!

Still don't see how they're going to add in all the robots, plasma guns, alien genetics and anti-grav-enabled-parkour.


...oh wait, this is Battlefield, not Call of Doody.

Just a thought, if you anthropomorphize the planet...if you imagine that disease and other natural human limiting factors are a planets immune response...at what point do we become a virus. Just like in the video, it's horrifying to imagine an organism invading a cell and using it as camouflage. What type of virus do we become when we rewrite the genetic code of other organisms, resulting in our unchecked growth which eventually destroys the host?

I'm sure that malaria would think it unethical not to evolve in a way that would ensure the survival of future generations.

Kurzgesagt - CRISPR Genetic Engineering Changes Everything has been added as a related post - related requested by Mordhaus.

Boosting this quality contribution up in the Hot Listing - declared quality by Mordhaus.