*dead giraffe, lion happy with taste for blood, receptors firing again.

I agree with ya.

There are a lot of jumping to conclusions and pseudo-scientific & "spiritual" & "mystical" hyper-babble in there.

It's really not about being "right" about anything; I think when people go on their spiels about it - there is a lot of personal fervor and frustration that this is obviously something extremely important to study because it "seems" like the "impossible". That it is so impossible to describe that it seems like anything or everything. Even when I think about times I have been under it and try to imagine what it was like I feel like I am going to bust reality wide open.

I do believe that it is bizarre that this chemical exists and seems to interact with us in an extremely intense and vivid way. It will be interesting to find out what scientists find out about this thing in the next 50 years and hopefully they can figure out more than "It is attaching to 5-HT_ & 5-HT_ receptors".

In 2013 scientists found that a rat's pineal gland contains this molecule so the future is going to be pretty interesting on this topic.

People hear that the flicker fusion threshold is about 16hz, and that movies play at 24hz so they assume that there must be no benefit to higher framerates. Ofc, movies have a lot of motion blur to make the movement appear more smooth and quite often a TV will have sophisticated tech to make the lower framerates on TV shows appear smoother than they actually are. Computer monitors, for the most part, show sharp images and we sit closer to them so low frame rates are much more noticeable. The rods and cones in our eyes might have a "fresh rate" of 16hz (I think rods actually respond much faster, but w.e) but they aren't synchronised like a camera. Our eyes will detect light, or any changes in it pretty much instantaneously. You don't have to wait for the next refresh. At what point our brain, or the variance in latency of the optic nerve, become the limiting factors I don't know. I'd like to think we wouldn't have evolved such advanced optical receptors only to be bottle necked by our brains. In short: 120hz ftw.

My absolute greatest peeve with console ports is mouse settings though. The number of times I've had to delve into the .ini to disable mouse acceleration or set my sensitivity to something sensible. Sometimes even the .ini doesn't have the answer. I fucking hate it when you get a sensitivity slider with 10 arbitrary notches. "Don't worry gamers, I'm sure you'll find a setting you like. As long as your preference is for a mm of mouse movement to spin you between 360 and 720 degrees. Ps. you do have a gamepad rite?"

As you say, "Fuck you" indeed.

Hmm. This could have been done better. I was hoping to see visualizations of:
* Birds' extremely high-speed vision; fast enough to fly through trees' foliage.
* Jumping spiders with 2 focusable main eyes and 6 other eyes.
* Mantis shrimp with their 6+ receptors, including UV, IR and polarization.

Alright,

this Wikipedia entry is a good start on the neuroscience and chemistry that goes on inside our brains when love happens:
http://en.wikipedia.org/wiki/Biological_basis_of_love

As for the chemistry of conciousness, I'd recommend the book Neurochemistry of Consciousness: Neurotransmitters in Mind. I believe it's a free download on most readers. It's also a neat read.

It is exciting that we are those things. Because we all have roughly the same physical materials in our head, and we are all different people. The majority of us have the ability to record, interpret and recall information and stimulation, and it's all those chemicals and receptors in our heads.

We fall in love, or hate, or feel "meh" about something because of the stuff in our brain that makes our personalities. Even identical twins are still different people. That's amazing to me. The fact that we even reproduce at all, it takes a lot of work on a cellular level to even have a kid. That is amazing to me.

I have yet to see any proof that this is a god or a soul. What we can do is, look inside someone's brain and measure what's happening and what reactions we have. We can see it, we can observe and form conclusions from it.

We know that if you give a type I diabetic insulin, that insulin will act as a replacement inside their body. We also know, from the news, that if you try and think positive about getting that pancreas to work again, it fails to do so.

So, when someone says, that spirituality can cure disease, all I ask for his some hard proof. Not a bunch of hokem.

CBD possesses sedative properties (Carlini and Cunha, 1981), and a clinical
trial showed that it reduces the anxiety and other unpleasant psychological
side effects provoked by pure THC (Zuardi et al. 1982). CBD modulates the
pharmacokinetics of THC by three mechanisms: (1) it has a slight affinity for
cannabinoid receptors (Ki at CB1 = 4350 nM, compared to THC = 41 nM,
Showalter et al. 1996), and it signals receptors as an antagonist or reverse agonist
(Petitet et al. 1998), (2) CBD may modulate signal transduction by perturbing
the fluidity of neuronal membranes, or by remodeling G-proteins that
carry intracellular signals downstream from cannabinoid receptors, and (3)CBD
is a potent inhibitor of cytochrome P450 3A11 metabolism, thus it blocks the
hydroxylation of THC to its 11-hydroxy metabolite (Bornheim et al. 1995).
The 11-hydroxy metabolite is four times more psychoactive than unmetabolized
THC (Browne and Weissman 1981), and four times more immunosuppressive
(Klein et al. 1987).
CBD provides antipsychotic benefits (Zuardi et al. 1995). It increases dopamine
activity, serves as a serotonin uptake inhibitor, and enhances norepinephrine
activity (Banerjee et al. 1975; Poddar and Dewey 1980). CBD protects
neurons from glutamate toxicity and serves as an antioxidant, more potently
than ascorbate and α-tocopherol (Hampson et al. 1998). Auspiciously, CBD
does not decrease acetylcholine (ACh) activity in the brain (Domino 1976;
Cheney et al. 1981). THC, in contrast, reduces hippocampal ACh release in
rats (Carta et al. 1998), and this correlates with loss of short-term memory consolidation.
In the hippocampus THC also inhibits N-methyl-D-aspartate (NMDA)
receptor activity (Misner and Sullivan 1999; Shen and Thayer 1999), and
NMDA synaptic transmission is crucial for memory consolidation (Shimizu et
al. 2000). CBD, unlike THC, does not dampen the firing of hippocampal cells
(Heyser et al. 1993) and does not disrupt learning (Brodkin and Moerschbaecher
1997).
Consroe (1998) presented an excellent review of CBD in neurological disorders.
In some studies, it ameliorates symptoms of Huntington’s disease, such
as dystonia and dyskinesia. CBD mitigates other dystonic conditions, such as
torticollis, in rat studies and uncontrolled human studies. CBD functions as an
anticonvulsant in rats, on a par with phenytoin (Dilantin, a standard antiepileptic
drug).
CBD demonstrated a synergistic benefit in the reduction of intestinal motility
in mice produced by THC (Anderson, Jackson, and Chesher 1974). This
may be an important component of observed benefits of cannabis in inflammatory
bowel diseases.

--"Cannabis and Cannabis Extracts:
Greater Than the Sum of Their Parts?
John M. McPartland
Ethan B. Russo"

This track....Has such the groove that hits on all receptors, love that cover, thanks lurgee!

From Wikipedia:
Adalimumab (HUMIRA, AbbVie) is the third TNF inhibitor, after infliximab and etanercept, to be approved in the United States. Like infliximab and etanercept, adalimumab binds to Tumor necrosis factor-alpha (TNFα), preventing it from activating TNF receptors. Adalimumab was constructed from a fully human monoclonal antibody, while infliximab is a mouse-human chimeric antibody and etanercept is a TNF receptor-IgG fusion protein. TNFα inactivation has proven to be important in downregulating the inflammatory reactions associated with autoimmune diseases. As of 2008 adalimumab has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, moderate to severe chronic psoriasis and juvenile idiopathic arthritis. Although only approved for ulcerative colitis from late 2012 by the FDA in the disease's management, it has been used for several years in cases that have not responded to conventional treatment at standard dosing for Crohn's Disease.

But yes, seeing a powerfull and potetially extremly harmful drug advertised for what seems to be (I am no medical expert) a "cosmetic disorder"is frightening.

Simple as fear. It is not only a wonderful experience it is also very terrifying. Psychedelics, if that is even what it is, have been ostracized by society, for whatever reason, politics, philosophy, culture, people making OSs due to their inspiration since the 60s. DMT was known about back then, but not widely known about, back then it was super rare. Getting the main ingredients would have been a pain and required going to South America.

Now that the ingredients are not difficult to get, thanks to the digital information system, more and more people are seeing what this thing is. And many of them that take enough come back with stories right out of a Phillip K Dick novel, or information that seems so New Agey, frequencies, cymatics, fractals, entities, etc, it is too weird or difficult for people to even want to look at this as something more than a really crazy drug and look into what it is doing to the brain. This has been done to small extents in providing details into which serotonin receptors DMT is affecting. What is clear is that one would have to take HUGE amounts of mushrooms to get to what this state is, if it is even possible. This takes a person there in two seconds then ten minutes, you are back. How is it possible?

By all means, I would LOVE for this to be studied by science ; then the Singularity would be right around the corner, mann...JK.

What is religion anyway? Many of them exude the same principles of which I believe have some truth in all of them. Hinduism and Buddhism probably moreso than others but that is just me and what I have seen and learned.

Though there is definitely more verifiable truth to Math and Science. We were built and evolved in this intergalactic system, a system largely devoted to geometry... and an intergalactic system that we do not know much about.

We hardly even know how our brain functions and even less about the subconscious or what happens when we sleep, we know these aspects of our own being impact us, we can study the brain waves, we can hypnotize, we can slip in different molecules into our serotonin receptors, but we still do not understand why. It is a mystery yet to be solved. Much like this phenomenon we might believe as God. Eventually, I believe that we can figure out the science and it will be mindbogglingly simple creating much complexity. Akin to a simple formula as x=abs(x) or y=abs(y) or m=x*x+y*y or x=x/m+cx or y=y/m+cy. But, math will not contain the science of all of the states of being, spirit realms, and matter that do not relate to us on Earth. In my opinion this is only one life. The science of the next could be completely different.

Is God a deity or a they? The programmers of a gigantic reaction that occurs probably in many more places than we can imagine. Who are connected to everything. Maybe, it was a blob of energy that never knew it could create consciousness and the Earth evolved us to be conscious to protect it. Yeah, great job guys.

No one has that great of an idea because if it is real, it would be absolutely mind blowing and beyond all human comprehension, yet probably very simple once we understood it. There is only one way I know to reach out and touch a little bit of it on Earth and it is absolutely amazing and terrifying all at the same time and beyond human linguistics. Science so far is hardly trying to figure it out but it is science, because if all living things ingest this molecule that resides in everything and then is able to see through dimensional portals, into afterlife, through the universe, think it is dead because it is impossible otherwise... well that is Spirit Science something of which is only beginning to come to fruition.

I just think everyone is somewhat right, even Christianity, hehe, as long as they are teaching compassion and love; there is something to it be it group therapeutic, psychological, or really there is something much bigger going on that science has no way of quantifying. Again, I am not saying anyone is right or wrong but that there are truths in everything and to completely disregard them might not be the best approach, even if it is an amalgamation of prior knowledge so very twisted by imperialists throughout these two thousand plus years.

Science is what we need to get behind to begin unraveling these mysteries, even though it is a slow process. I bet that science will eventually grapple to learn that these mystical underpinnings of religions, cults and ancient sacraments... these things Christians call holy light, prayer, God, resurrection, afterlife, angels... fit into the coding of the universe. If string theory and quantum mechanics did not already open that can of worms up. But, I also doubt that whoever created this thing that we are, wants to be seen and would have put up many barriers, knowing full well that its creations would seek them or it out. Or maybe it is the exact opposite....

If you happen to be one of those people without a so-called, "additive personality" but enjoys the occasional fiend-fest you can enjoy all those imprinted receptor-pops with satisfying moderation.

I ❤ Opiates and adrenaline

...oh and dopamine. Dopamines' good.

that would be my variation of dystop's instructions regarding suggested ingredients...works well in a hundred different variations, hits on all six tongue receptors no matter how you mix it...

I found these to be presumptuous. They do happen to some people, maybe even most people, but they don’t happen to all. Many people of no religion, and despite immense tragedies, live happy and fulfilling lives, and feel happy and fulfilled on their death beds. I’d further argue that people with religious faith also get depressed. I suspect you’d counter that anyone who is depressed has insincere faith. That seems tautological to me, but either way, it’s moot, for now.

Well, the central argument of the video is that life without God is meaningless. You've already agreed with that point, so the argument now seems to be is whether someone can be happy and fulfilled with a meaningless life. I'm sure there are plenty of people who weren't believers who died happily in ignorance of the truth, but the question is, did they understand that their life was meaningless? I doubt it. It is not something that many people are able to face, and even if they could, they certainly don't live that way. In some way or another, they are deluding themselves and living as if their life does have meaning.

Some people do, at least in part. It’s a lot more complex than just a lack of hope though. For some people it’s due to a tragedy, or overwhelming cognitive dissonance, or it’s simply chemical, and has no correlation with anything in their lives at all. Maybe I’m nitpicking. I just want to make clear that depression is a mental disorder and is not a synonym for, "lack of hope because I don’t have God in my life."

Hope is what keeps people going. Without hope, you are just going through the motions. When you have hope and lose it, it is emotionally devastating. A person without any hope is a person most likely clinically depressed.

You can call depression a kind of mental disorder, and some people may be born without the right chemical receptors for instance, but most people are depressed because of a lack of hope. A person, for instance, who worked their whole life and lost their retirement in an afternoon, or a mom whose kids abandoned her to live in a nursing home. They are not mentally ill, they are simply facing the cold, stark reality of their situation.

Here you slipped into metaphysical talk that means nothing to me, full of judgemental words ("sick and depraved") and terms that I had just told you I don’t accept as objective concepts ("evil"). You also know that I don’t think there’s any hope in your Yahweh God since he’s a mythological character, so I’m not sure where that’s coming from.

The point being, that if there is no God then no one is in the drivers seat here on planet Earth. I would be surprised if the extreme fragility of our civilization escaped you. If you look at history, and you contrast it to what is going on today, you will find that the new is simply the old in different packaging. We're watching the exact same game show, simply on a grander and more dangerous scale. Humanity has never been closer to utterly destroying itself anytime in its history than it is today. I'm sure, like everything else in creation, you will attribute that to dumb luck. However, if you think everything is a numbers game, then sooner or later the odds say that cooler heads will not prevail and there will be a civilization annihilating calamity. The truth is, it is only the sovereign hand of God that is restraining this from happening.

The reason I made that comment about God is because of your comment about your depression. The reason you have that feeling that if you believed in God you wouldn't be depressed is because you know there is hope in God.

(Also, not that it’s critical to the discussion, but I’d like a reference for your poll about young people not knowing who Hitler was.)

http://www.huffingtonpost.co.uk/2012/06/29/half-german-teens-dont-know-hitler-dictator_n_163659 3.html

Now, about "bliss". I didn’t define what I meant by that, so you didn’t understand it. I’ll make up for that now. By “bliss”, I don’t mean immediate pleasure, or instant gratification, or fulfillment of a goal, or basically anything you mentioned. I do mean a great powerful feeling of being centred, being in tune, achieving self-fulfillment, overflowing joy, love, inner peace, elation, connection, lightness, "harmony", "rapture" or a feeling that many describe as "doing what I was born to do/meant to be doing" or "transcendent". It’s the kind of happy that boosts your immune system and makes people around you feel good about themselves as well. (The words in quotes aren’t words I tend to use myself—I’m employing them to help clarify the concept I’m talking about.)

If you understand now what I mean by "bliss" (as opposed to instant gratification, etc.), you’ll understand that people don’t follow their bliss and rape people, nor find inner peace by beating their wives, and so there’s no need to append any rules about not hurting. I can’t imagine how anybody’s bliss could ever include causing harm to other people, but I’ll even address that hypothetical, towards the end of this comment.

Thanks for the elaboration. I am familiar with the philosophy of Sam Harris, and I figured you were borrowing from him, but it is good to know where you stand. My original point, however, still stands. You say you can't imagine someone finding bliss in hurting people. Well, have you ever heard of psychopaths? They do indeed find their bliss in acquiring power and control and making other people miserable, and they feel absolutely no remorse for doing so.

You also say that you feel the best state of a human being is to be blissfully happy. I'm sure everyone will agree with you that feeling blissfully happy is good. However, why should we believe this is actually what good is?. Yes, it feels good to feel good, but this doesn't tell us why we *ought* to do anything. Maybe this is just incredibly selfish and the opposite of good, or somewhere in the middle is true, or maybe none of it. You give no actual reason (beyond arbitrary statements like that which makes the world better or worse) to equate feeling good with moral goodness. In a meaningless Universe, neither is there any basis for thinking that you have any moral duties. This leads me to some questions that you didn't actually address in the last post. Let me ask them again because they are central to this discussion:

In a meaningless Universe there is no actual right and wrong, so why shouldn't you just do whatever you want? Why waste your time trying to navigate some moral landscape that you don't even believe really exists? Why not just take what you can, when you can, before you lose the opportunity?

I'll also address some of your comments:

In all cases, whatever they did, it was because they were feeling bad about something, weren’t centred, and reacted from "lizard brain" instincts of individual survival rather than from human compassion

People do evil because they get carried away by their lusts and become enticed. You view this as some sort of ignorance, or automatic function. Not so. When a person is doing wrong, they are almost always entirely aware of this, but simply override their moral restraints with their desire to fulfill their lusts. People are responsible for the evil that they do, not society, environmental factors, their parents, or anything else.

Divine morality isn’t necessary. Having any collective understanding of what is good and what is bad is enough. For most of humanity’s existence, even up to now, there hasn’t been a clear standard. In patches of geography where there was one, it only applied well to that time and culture. Just as ordinary people supplanted kings and emperors as absolute leaders without society collapsing, and just as ordinary people supplanted religions are sole arbiters of the law without society collapsing, ordinary people can supplant religion as arbiter of what is good and what is bad as well, and society will continue not to collapse.

I've already agreed with you that we all have a God given conscience that tells us right from wrong. Therefore, we don't need to read the bible to know that it is wrong to murder or steal. However, what God has commanded is that we all repent and believe in the gospel. This is something you aren't going to intuitively understand without being told.

And better than a list of what’s good and what’s bad is a system that determines for us what’s good and what’s bad. I’ve seen one model that I like, delivered by Sam Harris. The most salient bit starts at about 10:00 and runs to around 27:30. If you don’t want to watch it now, I’ll summarise the most important ideas: For a moral code to have meaning, it has to apply to some form of consciousness – it cannot apply to rocks and dust. Then there’s the central point which requires you to imagine "the worst possible misery for everyone", and assume that this situation is "bad". "Good" is then defined in terms of moving people away from this "worst possible misery for everyone". That’s it. I recommend hearing it from Harris himself.

I am familiar with his system, to which I reiterate the point; what is the ground for associating moral evil with misery and moral good with "moving people away from misery". Where do you get moral duties in a meaningless Universe?

The three advantages that occur to me of this system over Yahweh’s morality are that it’s a simple system rather than a long intricate list, so it’s quick to teach, easy to absorb, understand and reference, hard to corrupt, and all-inclusive; there’s absolutely nothing random about it, so odd details like not being allowed to wear garments made from two different thread types won’t make it in and there’s nothing objectionable about it from the standpoint of people who just want to do the right thing; and it’s truly universal in that it applies equally well now as it would have in 4000 BC China, in 30 AD Mesopotamia, or will in 12 000 AD Mars, so it’s broadly acceptable too.

The morality that God gives can be summed up in two commandments: Love the Lord thy God with all thy heart, and all thy soul, and all thy mind and all thy strength, and love thy neighbor as thyself. As Jesus told us:

Matthew 22:40

All the Law and the Prophets hang on these two commandments

That's a very simple system. When you love God and other people everything else follows naturally.

Every act that is good makes things better for people. If an act makes the world worse, then it’s bad. Simple. Lots of generalities can be derived from it, like killing people is bad, respecting other people’s property is good, and there’d be no arbitrary crap about touching pig skin being bad or extra-marital sex being bad.

On the contrary, it's all arbitrary, because "what makes things better for people" or what "makes the world worse" is something determined by consensus. If everyone in the world agreed that torturing babies for fun made things better for people, it would be good in your view. If your moral system allows for this possibility, I think that's a sign its time to throw it away.

Even more generally, we clearly don’t require any god to tell us what’s good and what isn’t. We already have a conscience inside us that tells us what’s good and what isn’t regardless of laws. I know you believe that Yahweh made our conscience for us. Even if that were so, it doesn’t change the fact that if properly relied upon, a conscience precludes the need for an external set of laws. Any law that echoes what everyone naturally feels already is superfluous. Any law that contributes to human misery is morally wrong and deserves to be disregarded.

If this were true, there would be no need for courts, judges, prisons, or police officers. There are also laws which may make some people miserable but are necessary for the greater good.

You state that without a divine moral standard that exists outside our consciousness, there is no objective justice. This is true by definition. Without a true objective moral code, you further argue that nobody can condemn any action as bad without being hypocritical, so in effect, everything is permissible. This is not the case, however. Although the moral code I advocate isn’t "objective" in the sense that it exists beyond our consciousness, it is universal among humans. And if we’re only attempting to determine moral behaviour for humans, then a universally accepted standard among humans suffices, regardless of where we think it came from.

It doesn't suffice, though. Yes, we can both agree there is a universal morality among human beings. How is that fact supposed to serve as grounds to invent an arbitrary system of good and evil based on people following their bliss and avoiding misery? I could just easily reverse the two and say the existence of universal morality justifies that too. I could say that the existence of a universal morality justifies that we should all love eggplants and hate rutabagas. There is no logical connection here between the system you've created and universal morality.

If there is no objective morality, then nothing is really wrong. Any system you create in the end is a human invention, based on human interpretation, and agreed upon by human consensus. You still cannot get an ought from an is. Good could be defined as a world of people who love each other, or a world of people who love to eat children. What is wrong then is simply based on your personal preferences.

The arguments I make here don’t describe a perfect system. That’s wasn’t my intention. I believe they do, however, answer your concerns about non-objective morality being insufficient to guide humans.

I understand that this wasn't meant to be perfect. It has, however, raised more concerns than it answered.

>> ^messenger

fish have no pain receptors. therefore no reason to scream. also means they make good bait for bigger fish and sometimes peta members.

>> ^Sarzy:

As someone whose genes pretty much guarantee I will eventually start balding, this intrigues me.


This technique doesn't sound very useful for you due not only to the difficulties they mention, but also because it wouldn't fix the underlying problem, which is that chemical signalling in your scalp is telling your hair cells to atrophy. What you'll probably need to do is wait for a drug that inhibits your natural levels of hormones such as Prostaglandin D2 (or it's receptor) in the scalp. This hormone (and a derivitive) seems to be the one that lead to baldness, so hopefully help is around the corner.

http://www.sciencedaily.com/releases/2012/03/120321143013.htm