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Gully goes where you think he shouldn't

Retroboy says...

When someone gets around to capturing stuff like this with dual GoPro's that can be played back through Oculus Rift, there will be a lot of vomit on PC keyboards.

P.S. 1:46 : Oh look there's a convenient cliff to push the guy with the vuvuzela off of.

reaction video to the Tesla Model S p85 D

reaction video to the Tesla Model S p85 D

Brittany Maynard - Death with Dignity

Sniper007 says...

TONS of things cure cancer. All day, every day. Doctors have no clue what cancer is. All they can do is cut, burn, or poison and cross their fingers.

I didn't say Cannabis was THE cure. It is A cure used by thousands with amazing efficacy. Everyone is different.

Here's 60+ studies for your perusal if you insist on the superiority of western scientific research:

"Cannabis, and the cannabinoid compounds found within it, has been shown through a large cannabisplantamount of scientific, peer-reviewed research to be effective at treating a wide variety of cancers, ranging from brain cancer to colon cancer. Below is a list of over 60 studies that demonstrate the vast anti-cancer properties of cannabis.
Studies showing cannabis may combat brain cancer:
Cannabidiol (CBD) inhibits the proliferation and invasion in U87-MG and T98G glioma cells. Study published in the Public Library of Science journal in October 2013.
Tetrahydrocannabinol (THC) can kill cancer cells by causing them to self-digest. Study published in the Journal of Clinical Investigation in September 2013.
CBD is a novel therapeutic target against glioblastoma. Study published in Cancer Research in March 2013.
Local delivery of cannabinoid-filled microparticles inhibits tumor growth in a model of glioblastoma multiforme. Study published in Public Library of Science in January 2013.
Cannabinoid action inhibits the growth of malignant human glioma U87MG cells. Study published in Oncology Reports in July 2012.
Cannabidiol enhances the inhibitory effects of THC on human glioblastoma cell proliferation and survival. Study published in the Molecular Cancer Therapeutics journal in January 2010.
Cannabinoid action induces autophagy-mediated cell death in human glioma cells. Study published in The Journal of Clinical Investigation in May 2009.
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Study published in Cancer Research in March 2008.
Cannabinoids and gliomas. Study published in Molecular Neurobiology in June 2007.
Cannabinoids inhibit gliomagenesis. Study published in the Journal of Biological Chemistry in March 2007.
A pilot clinical study of THC in patients with recurrent glioblastoma multiforme. The results were published in the British Journal of Cancer in June 2006.
Cannabidiol inhibits human glioma cell migration through an independent cannabinoid receptor mechanism. Study published in the British Journal of Pharmacology in April 2005.
Cannabinoids inhibit the vascular endothelial growth factor pathway (VEGF) in gliomas. Study published in the Journal of Cancer Research in August 2004.
Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. Study published in the Journal of Pharmacology in November 2003.
Inhibition of glioma growth in vivo by selective activation of the CB2 cannabinoid receptor. Study published in the Journal of Cancer Research in August 2001.
Studies showing cannabis may combat colorectal cancer:
Cannabigerol (CBG) can inhibit colon cancer cells. Study published in the Oxford journal Carcinogenesis in October 2014.
Inhibition of colon carcinogenesis by a standardised Cannabis Sativa extract with high content of CBD. Study published in Phytomedecine in December 2013.
Chemopreventive effect of the non-psychotropic phytocannabinoid CBD on colon cancer. Study published in the Journal of Molecular Medecine in August 2012.
Cannabinoids against intestinal inflammation and cancer. Study published in Pharmacology Research in August 2009.
Action of cannabinoid receptors on colorectal tumor growth. Study published by the Cancer Center of the University of Texas in July 2008.
Studies showing cannabis may combat blood cancer:
The effects of cannabidiol and its synergism with bortezomib in multiple myeloma cell lines. Study published in the International Journal of Cancer in December 2013.
Enhancing the activity of CBD and other cannabinoids against leukaemia. Study published in Anticancer Research in October 2013.
Cannabis extract treatment for terminal acute lymphoblastic leukemia of Philadelphia chromosome (Ph1). Study published in Case Reports in Oncology in September 2013.
Expression of type 1 and type 2 cannabinoid receptors in lymphoma. Study published in the International Journal of Cancer in June 2008.
Cannabinoid action in mantle cell lymphoma. Study published in Molecular Pharmacology in November 2006.
THC-induced apoptosis in Jurkat leukemia. Study published in Molecular Cancer Research in August 2006.
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Study published in Blood American Society of Hemmatology in July 2002.
Studies showing cannabis can combat lung cancer:
Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of Icam-1. Study published in Biochemical Pharmacology in July 2014.
Cannabinoids inhibit angiogenic capacities of endothelial cells via release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells. Study published in Biochemical Pharmacology in June 2014.
COX-2 and PPAR-γ confer CBD-induced apoptosis of human lung cancer cells. Study published in Molecular Cancer Therapeutics in January 2013.
CBD inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. Study published in the Journal of the Federation of American Societies for Experimental Biology in April 2012.
Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non–small cell lung cancer growth and metastasis. Study published in Cancer Prevention Research in January 2011.
THC inhibits epithelial growth factor-induced (EGF) lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Study published in the journal Oncogene in July 2007.
Studies showing cannabis may combat stomach cancer:
Cannabinoid receptor agonist as an alternative drug in 5-Fluorouracil-resistant gastric cancer cells. Study published in Anticancer Research in June 2013.
Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. Study published in the Journal of Cellular Biochemistry in March 2011.
Studies showing cannabis may combat prostrate cancer:
Cannabinoids can treat prostate cancer. Study published by the National Institute of Health in October 2013.
Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms. Study published in the British Journal of Pharmacology in December 2012.
The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications. Study published in the Indian Journal of Urology in January 2012.
Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. Study published in Anticancer Research in November 2011.
Studies showing cannabis may combat liver cancer:
Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma (CHC). Study published in Cell Death and Disease in May 2013.
Evaluation of anti-invasion effect of cannabinoids on human hepatocarcinoma cells. Study published on the site Informa Healthcare in February 2013.
Antitumoral action of cannabinoids on hepatocellular carcinoma. Study published in Cell Death and Differentiation in April 2011.
Studies showing cannabis may combat pancreatic cancer:
Cannabinoids inhibit energetic metabolism and induce autophagy in pancreatic cancer cells. Study published in Cell Death and Disease in June 2013.
Cannabinoids Induce apoptosis of pancreatic tumor cells. Study published in Cancer Research in July 2006.
Studies showing cannabis may combat skin cancer:
Cannabinoid receptor activiation can combat skin cancer. Study published by the National Institute of Health in October 2013.
Cannabinoids were found to reduce skin cancer by 90% in just 2 weeks. Study published in the Journal of Pharmacy and Pharmacology in July 2013.
Cannabinoid receptors as novel targets for the treatment of melanoma. Study published in the Journal of the Federation of American Societies for Experimental Biology in December 2006.
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. Study published in the Journal of Clinical Investigation, in January 2003.
Studies showing cannabis may combat other types of cancer:
Bladder: Marijuana reduces the risk of bladder cancer. Study published in the Medscape site in May 2013.
Kaposi sarcoma: Cannabidiol inhibits growth and induces programmed cell death in Kaposi sarcoma–associated herpesvirus-infected endothelium. Study published in the journal Genes & Cancer in July 2012.
Nose, mouth, throat, ear: Cannabinoids like THC inhibit cellular respiration of human oral cancer cells. Study by the Department of Pediatrics at the State University of New York, published in June 2010.
Bile duct: The dual effects of THC on cholangiocarcinoma cells: anti-invasion activity at low concentration and apoptosis induction at high concentration. Study published in Cancer Investigation in May 2010.
Ovaries: Cannabinoid receptors as a target for therapy of ovarian cancer. Study published on the American Association for Cancer Research website in 2006.
Preparation and characterisation of biodegradable microparticles filled with THC and their antitumor efficacy on cancer cell lines. Study published in the Journal of Drug Targeting in September 2013.
CBD Cannabidiol as a potential anticancer drug. Study published in the British Journal of Pharmacology in February 2013.
Cannabinoids as anticancer modulators. Study published in the Progress in Lipid Research journal in January 2013.
CBD inhibits angiogenesis by multiple mechanisms. Study published in the British Journal of Pharmacology in November 2012.
Towards the use of cannabinoids as antitumour agents. Study published in Nature in June 2012.
Cannabinoid-associated cell death mechanisms in tumor models. Study published in the International Journal of Oncology in May 2012.
Cannabinoids, endocannabinoids and cancer. Study published in Cancer Metastasis Reviews in December 2011.
The endocannabinoid system and cancer: therapeutic implication. Study published in the British Journal of Pharmacology in July 2011.
This list was compiled in part by Alchimiaweb.com.
– TheJointBlog"

ChaosEngine said:

No, you'd be remiss if you opined blatant misinformation.

While there is a possibility that cannabinoids can inhibit tumour growth, there is nothing even close to a solid evidence base to show that "cannabis cures cancer".

Enter Pyongyang

RedSky says...

I also found it interesting they highlighted the Ryugyong Hotel (the huge pyramid building). It's been under construction for 25 years, largely halted since the Soviet Union collapsed and the slush fund train ended. While the exterior is done according to wikipedia, the interior is not and it's always be unoccupied.

China's metropolises feed a similar misconception. They are similarly impressive that it's easy to forget that the country as a whole is still very poor. China's GDP per capita is half of Brazil, a quarter of South Korea and a tenth that of the US.

While China is obviously not as repressive as NK, the hukou dual citizenship system has a similar effect of segregation rural and urban dwellers. While rural workers may be able to move to work in the cities, they will enjoy none of the social benefits and protections that local citizens do. This has a lot to do with China's disparity of income and accretion of wealth to the large cities.

dannym3141 said:

Sadly yes, that's where all the favourables live. If you win the genetic lottery in NK, you get to eat and be comfortable. The fact that it's so developed is the reason why the rest of the country is left to rot; it's the only part that gets any attention, the only part anyone would let you see.

Shit! Shit, shit, shit!

Chairman_woo says...

He's not trying to lanesplit the trucks, he's panic braking because they have stopped and he was going too fast/noticed too late. He goes between them because there is no where else to go if you see what I mean.

It wasn't lane splitting that caused the problem it was noticing static traffic ahead too late (maybe going to fast to boot). Arguably all his fault anyway, but dual carriageways can catch you out like that sometimes (only takes a moment) and bike brakes are kind of shitbox.

Yogi said:

Lane splitting has been proven to be safer than not. NOT IN EVERY CASE YOU IDIOT! See giant trucks that can't see you, stay out of their way!

Jeff Zwart Pikes Peak Run, 2014 - /DRIVER'S EYE

Let's Grow Old Together... and Die at the Same Time

JAPR says...

Dig the dual vox at the end a lot. From this one song, sounds like something of a mix of the Cure and Joy Division. I'll have to check out an album, any recommendation, @lucky760?

Tailgating is bad, okay!

Chairman_woo says...

I feel like I can take a middleground on the whole tailgating issue, as a commuting biker I tend to experience both ends of the equation quite regularly and IMHO the problem lies in the extremes in attitude.

On the one hand if you drive/ride a lot and have good confidence in the vehicle and roadcraft in general (frequently the case with professional van and truck divers) it can be extremely frustrating when people don't practice good lane and speed discipline. I don't mean people maintaining a decent pace (it's your problem if you want to go faster than posted limits and they don't) I mean people either:
A. Driving below the posted limit (within reason)
B. Accelerating to speed absurdly slowly or slowing to 2mph to take a corner you could hit at 10-20 comfortably
C. Hogging the outside/passing lane because THEY are going as fast as THEY want to go so why should they speed up or slow down to get out of everybodys way? (C**TS!)

Under the above circumstances I understand why people end up tailgating, in fact I think it happens without much of a conscious effort most of the time. They are going so far below the pace the seems reasonable that you close the gap without realising. Getting to this stage is understandable/inevitable, it's what you do next that defines you as a responsible road user:

A responsible driver/rider at this point backs off, the point has already been made to the driver in front. They know they are going slower than you want to go or that you want to pass in the passing lane they are hogging. Sitting on their bumper is not only dangerous to both of you but it's obnoxious and likely to be counter productive. When you see someone driving too close your natural response is to slow down for safety or simply as a fuck you to the other guy. Even if you were about to get out of their way you might change your mind and think "screw you buddy I got the hint but now your just being rude".

When I back away I find people let me through far more often, wheras in the past when i've just tail gated them like a dick it's got me nothing but two angry motorists (and a hugely elevated chance of an incident). The lorry driver could have left a bigger gap but it didn't look that unreasonable (plus lorries have a hard time gaining speed and are naturally inclined (and taught) to preserve it where possible).

It might not be that unfair to suggest he was antagonising the car infront, but it pales into insignificance compared to...

.....the other side of the equation (which blue peugeot falls squarely into) who are generally IMHO far worse/more dangerous. The one's that adopt an imperious and selfish attitude to speed and road position. "I'm going as fast as I want to go and there's car on the inside that I'll pass in about 30seconds so I'm just going to sit in the outside lane going 2mph faster than slow lane traffic, because why should I have to go to the trouble of changing lanes to let someone else go faster than I want to go!"

Touching the brakes to give a tailgater a shock done properly is fine (I might even go so far as to recommend it) but holy shit! I think it'd be dangerous to scrub more than 1 or 2mph never mind an illegal stop on a dual carageway. Even if there was a mechanical reason for stopping it's still illegal to stop there without pulling off to the side.

Either way 45k in damages feels like pretty just deserts. I dearly hope he got at least a 12 month ban to boot. There's slipping up and then there's premeditated dangerous driving!

I usually try to see things from everybody's perspective when it comes to stuff like this but the Peugot driver is so disproportionately stupid and reckless than I can't really even try to defend him/her. I get why they might have been annoyed but that all became irrelevant the moment they tried to cause an accident!

Power Japan Plus - Dual Carbon Battery

aaronfr says...

Tell an engineer that you want a battery that’s powerful, safe, reliable, and cheap, and he’ll probably respond, “Powerful, safe, reliable, cheap: pick any two.”

It's "dual carbon" because both anode and diode are carbon. It is still a lithium ion battery, but it is much cheaper because most lithium ion batteries today use rare earth metals that are hard to mine, very expensive and difficult to recycle/dispose of.

So this battery might be cheaper and safer, but jury's still out on powerful and reliable.

newtboy said:

But didn't the video say the 'electrolyte' was still made of lithium ions? Maybe I missed something?
I want it to be a real, cheap, stable, eco-friendly, powerful battery, but I have to wait to see it for sale and in action first.

rayok (Member Profile)

Colonel Sanders Explains Our Dire Overpopulation Problem

RedSky says...

@ChaosEngine

While long term, it is continuous, relatively easy to encourage (than directly constrain population growth) and historically effective.

As for resources consumption, see my posts about automatic adjustment, comparison to nuclear family, fallacy of fixed factors in an economy etc ... If you disagree with any of these, why?

@gorillaman

Which is politically infeasible, short of a dictatorial state like China.

At this point there are no significant physical resources that you have pointed out that are genuinely becoming scarce. If they were, we would see prices sky-rocket and an adjustment away to another type would take place.

I gave the example of labour resources becoming scarce and the adjustment to dual income households. That was a gradual adjustment.

But okay, suppose energy resources genuinely became scarce. Current alternative energy (nuclear/renewable) techniques are not as cost effective as coal/gas/oil. But if there were genuine scarcity in fossil fuels, they would be.

We would know about the coming scarcity for at least a decade ahead and would build out alternative capacity over that period. Even if the average cost were twice current energy costs, how would that be different to the change to dual income households? Society wouldn't like it, but we would adjust.

Perhaps there may be some unrest in borderline developing/poor countries, especially those dependant on energy exports. But there would be no incentive for inter-country wars. In fact, those with the most efficient renewable technology would have much to gain from trading and selling their technology to those who do not.

Industrial Shredder Porn

chingalera says...

Well it ain't that the shredder's fault, eh? What, should your comment to the world suggest a challenge of sorts, or are ya a bit pissy today?? Guarantee ya that the Dual-Shear® M160 will fly right past the slate challenge....Ya seen what it can do with engine blocks??

eric3579 said:

That was weak. Pool table without slate is not a pool table.

New Wolfenstein: The New Order trailer

Bloom Boxes

chingalera says...

Wind turbines to provide the comparable megawatts for millions of homes ARE a frivolous waste. The huge amounts needed for wasteful, programmed, energy-addicted peeps IS a huge logistical clusterfuck of resources there, notarobot.

Your example of one family with a turbine and a solar array is fine and all (the upfront cost for such a setup is a shitload of funds and the upkeep of his dual set-up is probably a complete bitch of a money-pit to maintain) but were talking efficiency for the masses here.. Your 'research' should be based upon something besides what seems more of an emotionally passionate ideal moreso than anything practical for the many.

Personally, I think this virgin-trail-run Bloom box bullshit is simply another snake-oil scam. Much more work need be done to ever make them practical. What really should done in the realm of a practical kind of "reality" (otherwise known as a construct...reality that is) is to revive anti-trust/monopoly laws to hobble the robber-baron's once again...

Go listen some Bucky Fuller perhaps and try to awaken from the pipe-dream of monkey-business-as-usual instead of towing some lazy cop-out nouveau-hippy green-party line??

notarobot said:

A friend of mind put a windmill up on his property with a solar array and is completely off grid now. No more power bills.

To date I've seen no such data to make me feel that windmills are a waste or frivolous. Feel free to provide some figures and links.



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