Mixing 'em as we speak!

There is parts of this video that I agree with, and parts with which I must disagree. The truth is that yes, there are antibiotics and drugs that do not interact with each other when mixed with alcohol, but here is the reason with which it is advised against mixing the two:

Many, many drugs are metabolized in the liver. One of the many effects of acute alcohol intake will put a strain on your liver and occupy enzymes that would be otherwise used for digestion of the drug you are taking. This has an effect on the availability the drug to bind to these and alters the number of metabolites of that drug in the body (either increased or decreased).

Changes in the blood concentration of active metabolites may alter the effects and side-effects of that particular drug. This may reduce drug effectiveness or increase rate and intensity of side-effects.

Of course none of this may happen, but we advise you NOT to mix these drugs with alcohol in order to ultimately reduce the risk to the patient.

The poster was careful to keep 'antibiotics' specifically in the title.

I imagine the reason doctors say "don't take medicine with alcohol" is because this simplifies explaining which ones should be fine (most antibiotics) and which ones won't be (most everything else), with the worst result being that you don't drink as much as you would normally (vs. accidentally drinking with the wrong one and ending up with liver problems).



>> ^Tymbrwulf:


Changes in the blood concentration of active metabolites may alter the effects and side-effects of that particular drug. This may reduce drug effectiveness or increase rate and intensity of side-effects.
Of course none of this may happen, but we advise you NOT to mix these drugs with alcohol in order to ultimately reduce the risk to the patient.

Hrm, why does Fry still have that long-haired guy on the show?

>> ^bamdrew:

The poster was careful to keep 'antibiotics' specifically in the title.
I imagine the reason doctors say "don't take medicine with alcohol" is because this simplifies explaining which ones should be fine (most antibiotics) and which ones won't be (most everything else), with the worst result being that you don't drink as much as you would normally (vs. accidentally drinking with the wrong one and ending up with liver problems).


I'm just arguing the fact that the original reason might have been "tradition" but currently, it is the consensus of all doctors to reduce risk where we can. This is why we use "don't drink with alcohol" as a blanket statement. Alcohol is, after all, a drug.

Mixed 'em last night. I've never heard that you weren't supposed to mix them.

I never drink with alcohol, I drink alone.
*forever alone*
>> ^Tymbrwulf:

>> ^bamdrew:
The poster was careful to keep 'antibiotics' specifically in the title.
I imagine the reason doctors say "don't take medicine with alcohol" is because this simplifies explaining which ones should be fine (most antibiotics) and which ones won't be (most everything else), with the worst result being that you don't drink as much as you would normally (vs. accidentally drinking with the wrong one and ending up with liver problems).

I'm just arguing the fact that the original reason might have been "tradition" but currently, it is the consensus of all doctors to reduce risk where we can. This is why we use "don't drink with alcohol" as a blanket statement. Alcohol is, after all, a drug.

Crappy science on this vid, depending on the antibiotic there can be pretty severe interactions. Metabolic and liver issues are way at the top of issues:

http://www.questia.com/googleScholar.qst;jsessionid=A7B5A5594CC2FFDBED4D7A78457C6969.inst3_3a?docId=5002334780
http://www.mayoclinic.com/health/antibiotics-and-alcohol/AN01802
http://www.goaskalice.columbia.edu/5144.html

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The duration of this video has been updated from unknown to 2:12 - length declared by radx.