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C-note (Member Profile)

720 Ton Dragline Excavator Rescue From Island

The meaning of birthstone on personalized necklace

Dr Sanjay Gupta's CNN Special "WEED"

vaire2ube says...

CBD possesses sedative properties (Carlini and Cunha, 1981), and a clinical
trial showed that it reduces the anxiety and other unpleasant psychological
side effects provoked by pure THC (Zuardi et al. 1982). CBD modulates the
pharmacokinetics of THC by three mechanisms: (1) it has a slight affinity for
cannabinoid receptors (Ki at CB1 = 4350 nM, compared to THC = 41 nM,
Showalter et al. 1996), and it signals receptors as an antagonist or reverse agonist
(Petitet et al. 1998), (2) CBD may modulate signal transduction by perturbing
the fluidity of neuronal membranes, or by remodeling G-proteins that
carry intracellular signals downstream from cannabinoid receptors, and (3)CBD
is a potent inhibitor of cytochrome P450 3A11 metabolism, thus it blocks the
hydroxylation of THC to its 11-hydroxy metabolite (Bornheim et al. 1995).
The 11-hydroxy metabolite is four times more psychoactive than unmetabolized
THC (Browne and Weissman 1981), and four times more immunosuppressive
(Klein et al. 1987).
CBD provides antipsychotic benefits (Zuardi et al. 1995). It increases dopamine
activity, serves as a serotonin uptake inhibitor, and enhances norepinephrine
activity (Banerjee et al. 1975; Poddar and Dewey 1980). CBD protects
neurons from glutamate toxicity and serves as an antioxidant, more potently
than ascorbate and α-tocopherol (Hampson et al. 1998). Auspiciously, CBD
does not decrease acetylcholine (ACh) activity in the brain (Domino 1976;
Cheney et al. 1981). THC, in contrast, reduces hippocampal ACh release in
rats (Carta et al. 1998), and this correlates with loss of short-term memory consolidation.
In the hippocampus THC also inhibits N-methyl-D-aspartate (NMDA)
receptor activity (Misner and Sullivan 1999; Shen and Thayer 1999), and
NMDA synaptic transmission is crucial for memory consolidation (Shimizu et
al. 2000). CBD, unlike THC, does not dampen the firing of hippocampal cells
(Heyser et al. 1993) and does not disrupt learning (Brodkin and Moerschbaecher
1997).
Consroe (1998) presented an excellent review of CBD in neurological disorders.
In some studies, it ameliorates symptoms of Huntington’s disease, such
as dystonia and dyskinesia. CBD mitigates other dystonic conditions, such as
torticollis, in rat studies and uncontrolled human studies. CBD functions as an
anticonvulsant in rats, on a par with phenytoin (Dilantin, a standard antiepileptic
drug).
CBD demonstrated a synergistic benefit in the reduction of intestinal motility
in mice produced by THC (Anderson, Jackson, and Chesher 1974). This
may be an important component of observed benefits of cannabis in inflammatory
bowel diseases.

--"Cannabis and Cannabis Extracts:
Greater Than the Sum of Their Parts?
John M. McPartland
Ethan B. Russo"

Sufjan Stevens - Jacksonville

MrFisk says...

I'm not afraid of the black man running
He's got it right he's got a better life coming
I don't care what the captain said
I fold it right at the top of my head
I lost my sight and the state packs in
I follow my heart and it leads me right to Jackson

Oh Keller oh oh oh
She gave us a medal she gave us a map
Oh Canner Row, oh oh oh
If seeing is right, then look where you're at

I'm not afraid of Nichol's Park
I ride the train and I ride it after dark
I'm not afraid to get it right
I turn around and I give it one more try
I said things that I meant to say
The bandstand chairs and the Dewey Day parade
I go out to the golden age
The spirit is right and the spirit doesn't change

Oh Keller oh oh oh
She gave us mirror she gave us a map
Oh Canner Row, oh oh oh
If seeing is right then look where you're at

Andrew Jackson, all I'm asking
Show us the wheel and give us the wine
Woohoo! Woohoo!
Raise the banner, Jackson hammer
Everyone goes to the capitol line
Woohoo! woohoo!
Colored preacher, nice to meet you!
The spirit is here and the spirit is fine!
Woohoo! Woohoo!
Education, ask the nation
You gave us our sight and the hearing is fine
Woohoo! woohoo!
Andrew Jackson all I'm asking
Give us the wheel and give us the wine

Dewey Dragonflies

PlayhousePals says...

>> ^Buck:

They eat mosquitos. I love them. They also were the reason I wanted to study flying helicopters...never did do that, but I watch them instead now.


They're doing a good job of that here ... there are hardly any mosquitoes that I've noticed being so close to the lake!

Dewey, from Malcolm in the Middle - on God

Dewey on God, morality and ants

Dewey on God, morality and ants

Religion (and Mormonism) is a Con--Real Time with Bill Maher

shinyblurry says...

Just because the universe might be eternal, does not mean that God is the automatic solution, nor the simplest explanation. That's just the one that makes sense to you. I would say that an eternal universe filled with rocks and gas is a little less complicated than an eternal, thinking, feeling, all-powerful being. But again, that's just my opinion. Those are large concepts, and the rules of physics, or even the seemingly bizarre rules of quantum mechanics do nothing to help explain them.

To me it is simply a probability argument. If you say that everything is equally unlikely, then if you strip away all other concerns, you just have the question..was the Universe deliberately created? The answer is either yes or no. You have evidence that perhaps there is design, which implies an intelligent (and powerful) creator. You have evidence that perhaps it could have happened by chance, by naturalistic processes. From there, you have to figure out what explanation best matches reality. You could ask, does something as wonderful as life and as amazing as the Universe just happen by itself? You could ask, am I just a bunch of atoms moving through space or is there something more to me than that?

Is an eternal God hard to grasp? Yes, but easier I think than something from nothing. If it is something from nothing we will always be ignorant of the initial conditions. If God created it, He will (presumably) educate us about the mystery of His existence. He promised this:

1 Corinthians 13:12

For now we see in a mirror dimly, but then face to face. Now I know in part; then I shall know fully, even as I have been fully known.

It is basically saying that God promises full disclosure when His Kingdom is established on Earth..

Occam's razor is simply a pragmatic way to find a solution, it does not prove anything, but just suggest what a likely answer might be. People use that argument about the complexity of universal laws all the time, but the fact of the matter is, we still don't understand 99.99999999% of the universe or how it works. We can see that if we "tweaked the dials", it would probably look much different than the universe we know, but there isn't a scientist out there in this world that could tell you with any certainty what would happen. Only that on a large scale, things might fall inward or burst outward faster, or that water might not congeal the same way.

Well, just in the initial conditions of the Universe, you have several values which just defy any naturalistic explanation. Even atheist scientists have to admit that a straight forward explanation indicates a designer:

Fred Hoyle, Astronomer said

"A commonsense interpretation of the facts suggests that a super-intellect has monkeyed with physics, as well as with chemistry and biology, and that there are no blind forces worth speaking about in nature. The numbers one calculates from the facts seem to me so overwhelming as to put this conclusion almost beyond question."

This has major implications for scientific theories, because it isn't simply a matter of it being incredibly unlikely, it is also matter of contradicting the predictions of standard models. I think you'll enjoy this article:

http://arxiv.org/PS_cache/hep-th/pdf/0208/0208013v3.pdf

Speaking of complexity, here's an exercise for your brain: Think about a mountain, on part of that mountain, pressure builds up, and a rock slide starts to fall. When it finally settles, the rocks, all the little pebbles and large boulders and particles of dust are arranged in just a certain way. Even though it's just a pile of rocks, it contains within it an inconceivable amount of complexity. Nowhere else in the entire universe, will there ever be a pile of rocks that have the exact specifications of this one. And even if it did, it wouldn't be composed of the same stone, And even if was, the elements that make up the stone wouldn't be arranged the same way. Nor would it be the exact same temperature, unless it was in the exact same relative position in the universe with an identical sun, with all the particles of gas and dust in between them arranged in exactly the same way.

In a way, the pile of rocks, when you think about it, is an impossibility. And yet it exists. There is no simple solution to explain it. An eternal creator, or the laws of physics? Either way, the true meaning is something that neither of us can comprehend. And to say that either one is "simpler" than the other is merely a statement of faith. Not fact.

Sure, taken by itself, such a thing is astonishing to behold. Divorced from its circumstances, it is perplexing to say the least. Yet, either explanation for the origin of this impossibility leads to a definitive conclusion. If it was naturalism, there is no meaning to it. It just happened that way and at best you can invent a meaning for it and decide to believe it. If it was created, however, it was created for a purpose. It has meaning because of that purpose; it is invested with meaning. In naturalism, you are practically looking at something alien. It is cold, dead, inexplicable, and doesn't care about you. Under creation, you are at the least staring this quote from Einstein dead in the face:

"I'm not an atheist, and I don't think I can call myself a pantheist. We are in the position of a little child entering a huge library filled with books in many languages. The child knows someone must have written those books. It does not know how. It does not understand the languages in which they are written. The child dimly suspects a mysterious order in the arrangement of the books but doesn't know what it is. That, it seems to me, is the attitude of even the most intelligent human being toward God. We see the universe marvelously arranged and obeying certain laws but only dimly understand these laws. Our limited minds grasp the mysterious force that moves the constellations."

I go a step further because I believe God has revealed a bit about his Dewey Decimal System, but essentially, I am in staring at this in awe and wonder. I think those rocks are amazing and startling, but I also praise God for making them that way.

>> ^Ryjkyj:
We love you too. (but it's a rough, heathen love)
Just because the universe might be eternal, does not mean that God is the automatic solution, nor the simplest explanation. That's just the one that makes sense to you. I would say that an eternal universe filled with rocks and gas is a little less complicated than an eternal, thinking, feeling, all-powerful being. But again, that's just my opinion. Those are large concepts, and the rules of physics, or even the seemingly bizarre rules of quantum mechanics do nothing to help explain them.
Occam's razor is simply a pragmatic way to find a solution, it does not prove anything, but just suggest what a likely answer might be. People use that argument about the complexity of universal laws all the time, but the fact of the matter is, we still don't understand 99.99999999% of the universe or how it works. We can see that if we "tweaked the dials", it would probably look much different than the universe we know, but there isn't a scientist out there in this world that could tell you with any certainty what would happen. Only that on a large scale, things might fall inward or burst outward faster, or that water might not congeal the same way.
Point being, just because we can tell that the universe would be different, doesn't mean that it was designed. It just means that it is this way.
Speaking of complexity, here's an exercise for your brain: Think about a mountain, on part of that mountain, pressure builds up, and a rock slide starts to fall. When it finally settles, the rocks, all the little pebbles and large boulders and particles of dust are arranged in just a certain way. Even though it's just a pile of rocks, it contains within it an inconceivable amount of complexity. Nowhere else in the entire universe, will there ever be a pile of rocks that have the exact specifications of this one. And even if it did, it wouldn't be composed of the same stone, And even if was, the elements that make up the stone wouldn't be arranged the same way. Nor would it be the exact same temperature, unless it was in the exact same relative position in the universe with an identical sun, with all the particles of gas and dust in between them arranged in exactly the same way.
In a way, the pile of rocks, when you think about it, is an impossibility. And yet it exists. There is no simple solution to explain it. An eternal creator, or the laws of physics? Either way, the true meaning is something that neither of us can comprehend. And to say that either one is "simpler" than the other is merely a statement of faith. Not fact.

I Think I Kinda Want It

I Think I Kinda Want It

I Think I Kinda Want It

Dewey the Cat-CBS Sunday Morning

Dewey the Cat-CBS Sunday Morning



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