Lymphoma and Death Instead of Red Flaky Skin? Sign Me Up!

You might die, but at least your corpse will have partially clear skin.

It is a sick joke that this isn't a sick joke.
siftbotsays...

Self promoting this video and sending it back into the queue for one more try; last queued Monday, June 10th, 2013 9:23am PDT - promote requested by original submitter lucky760.

articiansays...

That is insane. I think it's an example of a solution looking for a problem. Some Pharmaceutical company probably discovered the formula and this was the only application they could find for it. But hey! They let you know risks! It's up to you now consumer!

mxxconsays...

This is a bit misleading.
Those side effects could have had happened in 0.01% of test cases, but by law they are required to list them all.
So it's not like 50/50...

AeroMechanicalsays...

Oh, I don't know. Almost all drugs are a trade off between side effects and therapeutic effects. You gotta look at the statistics and play the odds. If bad psoriasis is really reducing someone's quality of life, it might be worth the risk.

The shady thing would be if there were some older, off-patent treatment that works just or nearly as well (maybe even better) but doesn't have the same side effects, and it wouldn't surprise me at all if that were the case.

wraithsays...

From Wikipedia:
Adalimumab (HUMIRA, AbbVie) is the third TNF inhibitor, after infliximab and etanercept, to be approved in the United States. Like infliximab and etanercept, adalimumab binds to Tumor necrosis factor-alpha (TNFα), preventing it from activating TNF receptors. Adalimumab was constructed from a fully human monoclonal antibody, while infliximab is a mouse-human chimeric antibody and etanercept is a TNF receptor-IgG fusion protein. TNFα inactivation has proven to be important in downregulating the inflammatory reactions associated with autoimmune diseases. As of 2008 adalimumab has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, moderate to severe chronic psoriasis and juvenile idiopathic arthritis. Although only approved for ulcerative colitis from late 2012 by the FDA in the disease's management, it has been used for several years in cases that have not responded to conventional treatment at standard dosing for Crohn's Disease.

But yes, seeing a powerfull and potetially extremly harmful drug advertised for what seems to be (I am no medical expert) a "cosmetic disorder"is frightening.

lucky760says...

Fatal infections, lymphoma, and other types of cancer, problems with blood, liver, and nervous system, as well as serious allergic reactions and new or worsening heart failure all probably didn't happen to just 1 really unlucky person in 100.

I know you're just throwing numbers out there, but that's also misleading. The truth is that regardless of test results, if you take the drug you have some unknown chance of suffering any or all of a long list of severe or even fatal side effects depending solely on your personal health and biology.

If you want to take that chance, go for it, especially if the risks are worth the potential reward to you.

To me, though, it's like swinging an axe to remove a mole from your forehead.

mxxconsaid:

This is a bit misleading.
Those side effects could have had happened in 0.01% of test cases, but by law they are required to list them all.
So it's not like 50/50...

direpicklesays...

Psoriasis is a lot worse than a mole.

lucky760said:

Fatal infections, lymphoma, and other types of cancer, problems with blood, liver, and nervous system, as well as serious allergic reactions and new or worsening heart failure all probably didn't happen to just 1 really unlucky person in 100.

I know you're just throwing numbers out there, but that's also misleading. The truth is that regardless of test results, if you take the drug you have some unknown chance of suffering any or all of a long list of severe or even fatal side effects depending solely on your personal health and biology.

If you want to take that chance, go for it, especially if the risks are worth the potential reward to you.

To me, though, it's like swinging an axe to remove a mole from your forehead.

mxxconsays...

Well, the only sensible thing to do is to look up clinical study of this drug to find the actual numbers and % of side-effects.
Perhaps for somebody who suffer physical pain from this condition some chance of side effects is an acceptable risk.

lucky760said:

Fatal infections, lymphoma, and other types of cancer, problems with blood, liver, and nervous system, as well as serious allergic reactions and new or worsening heart failure all probably didn't happen to just 1 really unlucky person in 100.

I know you're just throwing numbers out there, but that's also misleading. The truth is that regardless of test results, if you take the drug you have some unknown chance of suffering any or all of a long list of severe or even fatal side effects depending solely on your personal health and biology.

If you want to take that chance, go for it, especially if the risks are worth the potential reward to you.

To me, though, it's like swinging an axe to remove a mole from your forehead.

lucky760says...

Agreed. It's understandable if someone suffers enough that the potential risks are acceptable to them.

This commercial's selling point, though, seems to be "Oh darn, because your arms are red you're too embarrassed to go outside with all your friends who are having lots of fun. Take this medicine and *maybe* you'll be *partially* better in 4 months and you can wear short sleeves or maybe you'll die. Yay!"

mxxconsaid:

Well, the only sensible thing to do is to look up clinical study of this drug to find the actual numbers and % of side-effects.
Perhaps for somebody who suffer physical pain from this condition some chance of side effects is an acceptable risk.

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