The Silence of the Lambs is a 1991 film directed by Jonathan Demme and starring Jodie Foster and Anthony Hopkins. It is based on the novel by Thomas Harris, his second to feature Dr. Hannibal Lecter, a brilliant psychiatrist and cannibal serial killer. In the film, Clarice Starling, a young FBI trainee, is sent to see the imprisoned Lecter in order to ask his expert advice on catching a serial killer given the name Buffalo Bill, who is abducting women and skinning them.

Jonathan Demme won an Academy Award for Best Director. Jodie Foster and Anthony Hopkins both won Oscars for their roles as Clarice Starling and Dr. Hannibal Lecter, respectively. Hopkins' performance as Lecter remains the shortest lead acting Oscar-winning performance ever, as Hopkins is only on screen for a little less than 17 minutes in the entire film. The film won additional Oscars for Best Adapted Screenplay and Best Picture. The Silence of the Lambs is only the third (and most recent) film to win the five most prestigious Academy Awards (after It Happened One Night, 1934 and One Flew Over the Cuckoo's Nest, 1975).

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http://en.wikipedia.org/wiki/The_Silence_of_the_Lambs_(film)