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8 Comments
song77says...Medically it has its uses, its for the average Joe, you and me that it doesn't have benefits (unless your selling it). It can ruin lives, just like alcohol and many other similar drugs.
Mekanikalsays...A buddy of mine runs a collective and tries to get the highest CBD on certain strains. He said there's a lot of red tape involved in getting it properly tested and that there are several different CBD types, each targeting a different part of the body.
vaire2ubesays...naw, unlike most "drugs" that ruin lives as a property of their chemical interactions, cannabis is completely safe.
the only thing that will cause harm is exacerbating an existing medical condition that is prone to the hypertension, or actions taken while in an "unsafe" setting like toking up the first time while driving.
hardly a reason to worry about it, most therepeutically safe substance known to mankind, as well as the fact that even if medical use isnt the reason, recreational use with properly informed persons will result in no harm and possible benefit.
even if people started using it at the volume and frequency of alcohol, their lives would actually be made better because of the effects of the plant.
infuriating but the truth is finally coming out. the US has a patent on CBD since 2003 through the dept of health and human services for its antiinflammatory effects. .. and no one even knows about CBD, even really educated people who have the internet. its fucked up. See the TED sift about willful ignorance.
when it becomes easier to be informed then not, we will see a change. thats fucked up, but whatever im not like that. ill keep trying.
chingalerasays...What gets me and should get everybody mad as hell, is that it took Dr. Guppy here and a so-called news network to rile the alleged intelligentsia as to the 70-plus-year dupe of otherwise practical, common-sense humans. What a fucking ruse. The fact that CNN's latest ratings-blasting segments from Dr. Dickcheese here has the fans of reason gushing proves only that the duping of another generation is still alive and well.
I say we kidnap this tool Gupta and inject him with some black-tar heroin for a few weeks while he's tied to a fucking rusty, mattress-less box spring, then put his paltry ass on-set in front of the cameras...
vaire2ubesays...i think its a start and at least its on a major network and talked about, for once, by a "known" "medical professional" ... end quotes
but yea he could have gone one step further and contacted the people who know the truth, and encourage everyone to go to norml.org at the beginning and post the website on tv throughout show...
rick steves gets passed over but this guy is gettin air time... he totally toked up and is like, wtf am i doing with my life..... and not in a bad way, like alcohol makes you feel
vaire2ubesays...http://imgur.com/12j6T.png
vaire2ubesays...CBD possesses sedative properties (Carlini and Cunha, 1981), and a clinical
trial showed that it reduces the anxiety and other unpleasant psychological
side effects provoked by pure THC (Zuardi et al. 1982). CBD modulates the
pharmacokinetics of THC by three mechanisms: (1) it has a slight affinity for
cannabinoid receptors (Ki at CB1 = 4350 nM, compared to THC = 41 nM,
Showalter et al. 1996), and it signals receptors as an antagonist or reverse agonist
(Petitet et al. 1998), (2) CBD may modulate signal transduction by perturbing
the fluidity of neuronal membranes, or by remodeling G-proteins that
carry intracellular signals downstream from cannabinoid receptors, and (3)CBD
is a potent inhibitor of cytochrome P450 3A11 metabolism, thus it blocks the
hydroxylation of THC to its 11-hydroxy metabolite (Bornheim et al. 1995).
The 11-hydroxy metabolite is four times more psychoactive than unmetabolized
THC (Browne and Weissman 1981), and four times more immunosuppressive
(Klein et al. 1987).
CBD provides antipsychotic benefits (Zuardi et al. 1995). It increases dopamine
activity, serves as a serotonin uptake inhibitor, and enhances norepinephrine
activity (Banerjee et al. 1975; Poddar and Dewey 1980). CBD protects
neurons from glutamate toxicity and serves as an antioxidant, more potently
than ascorbate and α-tocopherol (Hampson et al. 1998). Auspiciously, CBD
does not decrease acetylcholine (ACh) activity in the brain (Domino 1976;
Cheney et al. 1981). THC, in contrast, reduces hippocampal ACh release in
rats (Carta et al. 1998), and this correlates with loss of short-term memory consolidation.
In the hippocampus THC also inhibits N-methyl-D-aspartate (NMDA)
receptor activity (Misner and Sullivan 1999; Shen and Thayer 1999), and
NMDA synaptic transmission is crucial for memory consolidation (Shimizu et
al. 2000). CBD, unlike THC, does not dampen the firing of hippocampal cells
(Heyser et al. 1993) and does not disrupt learning (Brodkin and Moerschbaecher
1997).
Consroe (1998) presented an excellent review of CBD in neurological disorders.
In some studies, it ameliorates symptoms of Huntington’s disease, such
as dystonia and dyskinesia. CBD mitigates other dystonic conditions, such as
torticollis, in rat studies and uncontrolled human studies. CBD functions as an
anticonvulsant in rats, on a par with phenytoin (Dilantin, a standard antiepileptic
drug).
CBD demonstrated a synergistic benefit in the reduction of intestinal motility
in mice produced by THC (Anderson, Jackson, and Chesher 1974). This
may be an important component of observed benefits of cannabis in inflammatory
bowel diseases.
--"Cannabis and Cannabis Extracts:
Greater Than the Sum of Their Parts?
John M. McPartland
Ethan B. Russo"
vaire2ubesays...wow it treats arthritis and makes grandma happy? fucking throw her in jail.
anti pot people are ... ignorant as fuck. willfully so. guess we just have to wait for them to die of cancer?
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