Caltech researchers Lulu Qian and Erik Winfree have managed to make 130 strands of DNA perform mathematical operations. And best of all, they have decided to popularize their result with a whimsical YouTube video!

Starts a bit slow, but visualizes the interesting process very nicely after a while.

Reference: "Scaling Up Digital Circuit Computation with DNA Strand Displacement Cascades," Lulu Qian and Erik Winfree, Science, June 3, 2011

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