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Neuroscientist Explains 1 Concept in 5 Levels of Difficulty

dubious says...

I'm a bit surprised the grad student or expert didn't discuss neuromodulators more. The fact is we already have the full connectome of a much simpler system, a worm (C Elegans). And this full mapping is considered insufficient to fully understand the simplified worm behavior because it doesn't fully capture the diversity of different neuromodulators and how they effect processing in neurons. It matters if the neuron is releasing dopamine, serotonin, glutamate, etc. There are ways to approximate these from EM images by analyzing the synapse properties, but ultimately it leads to a much larger problem in understanding neural processing.

In a similar light, the connectome project does not do a good job capturing synaptic strength. We don't really know just from the electron microscopy how strong the connections are. We can try and approximate it by looking at the size/formation of the synapse but ultimately this falls short.

For instance, my memory is that thalamocortical projections (thalamic nuclei to L4 of the cortex) do not make up the primary inputs to L4 on a structural connectivity level, but the strength of those connections are much stronger then the more numerous cortico cortical connections. I don't think the connectome from EM images will be able to pull that out.

The connectome is important, the same way knowing the human genome is important. However, it's really not going to tell us how to simulate a person. It's an important step to be sure, one we are still a good ways away from finishing last I checked (which was three years ago ...)

Carly's Cafe - Brilliant short about autism

Runaway Truck Causes Brutal Crash. 22 Dead.

chingalera says...

Yep-Doesn't belong here because like myself, a buncha folks can't stand that faces-of-death shit for the sake of entertainment or spectacle....it's fucking twisted as far as I'm concerned and deleterious otherwise to the psyche and soul to meditate on the same, voyeuristically-speaking....reflects a general lack of healthy socialization and higher-cortical function.

Get a fucking life, stop watching ambulances and listening to television news stories about the carnage, fires, wife-beatings and human suffering in your local area, and have a NICE goddamned day

Can I down-vote this fucking shit that's not snuff but sucks huge, bulging moose cock yet??

Joe Scarborough finally gets it -- Sandy Hook brings it home

chingalera says...

I don't have a problem with his statement-Though cliched to a degree the point is obvious and from the looks of your rant you've got personal issues with this user or his simplified statement of what should be obvious to anyone with a larger proportion of neocortex, with disproportionate enlargement of pre-frontal and temporal association cortices than lower apes.

"I love to eat it everyday, and if you ask me why I'll saaaaaaaayyyyyy...!" (fill in the last line with more baloney!)

TheFreak said:

Oh my! You are a tool. How about these gems while you're at it:

"Only from my cold dead hands"
"Molon Labe"
"I have a headache 'this big' and it has Excedrin written all over it"

...you know, since you're spouting marketing soundbites, might as well get all the classics in there.
How about, "my baloney has a first name, it's O S C A R,"

I'm beginning to suspect that the reason you never offer anything of substance in your comments isn't because you're an ideological conservative who staunchly believes in the right wing talking points...it's because you're an idiot who's easily taken in by simple rhetoric.

American girl flips the bird, throws drink in dudes face...

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