CRISPR-Cas9
Bring me a gene
Encoding for a specific protein
Make a few snips at this coded locus
You work so well inside a streptococcus
Cas9
I'm so alone
Without your scissors in my chromosome
Cut me up and do it clean
CRISPR-Cas9 bring me a gene

CRISPR-Cas9
Keep me a gene
A viral sequence you've already seen
Chopped into bits and stored as genomic
With clustered repeats
That are palindromic
Cas9
Bind with this code
Use it to target infections of old
Immunized like a vaccine
CRISPR-Cas9 keep me a gene

CRISPR-Cas9
Cut me a gene
With a precision that I've never seen
Unzip a strand and interrogate it
Seek out your sequence until you locate it
Cas9
Lock into place
And do your job as endonuclease
Chop just like a guillotine
CRISPR-Cas9 cut me a gene

Snip snap!
CRISPR-Cas9
CRISPR-Cas9

CRISPR-Cas9
Bring me a gene
By commandeering my repair routine
A strand to match your severed location
For some homologous recombination
Cas9
Cheap and precise
Rewriting genomes from microbes to mice
And soon the humble human being
CRISPR-Cas9 bring me a gene

CRISPR-Cas9
Give us a gene
Give us a miracle like that one Nazarene
‘Cause giving the lame their legs and the blind their sight is
In view for dystrophy and retinitis
But CRISPR-Cas9
What if you fall
Outside our power and inside us all
That really could incite a scene

When this terrible wonderful power unsettling
Opens the door to unethically meddle
Is ev’ry congenital malady bettered
Sufficient to warrant genetics unfettered
To modify man in the manner of Gattaca
Raise up a mammoth or make a rattata
Dramatical medical means to eradicate aging
Or cancer or make a fanatic
A mass epidemic a weapon nefarious
Single mosquito to wipe out malaria
Send in a viral infection to ferry a
Cure to the cells of an HIV carrier
Freed of disease as we're free to uncover
What nature and accident failed to discover
And free to be other than
All that we ever have been

CRISPR-Cas9
CRISPR-Cas9

Oh CRISPR-Cas9
Bring us a gene
You wondrous ribonucleoprotein
You have the power to vanquish or save us
Who would have thought that the microbe that gave us
Cas9
S. pyogenes
The source of strep and flesh-eating disease
Housed this marvellous machine
Full of uses great and obscene
CRISPR-Cas9 bring us
Please don't sting us
Cas9 bring us a gene

With adenine
And thiamine
Incite a scene
Cas9 bring us a gene!

she is sooooooooooo awful. throwing around false accusations just makes her look bad. and she speaks in obscenities to at least two people. oh my

i think this needs a control experiment with a fat guy in a string vest shouting obscenities to see if the cows come anyway

Wait! Did they just bleep the "hole" part of asshole. Does that mean you can say ass or hole but not hole in conjuction with ass. Would they bleep if he said anushole. Or could you say Trump is an ass and a hole and get away with it as long as you don't put them together. So sometimes an obscenity is determined by nothing more than a space. I'm confused.

I think perhaps your reading comprehension is lacking, not my logic.
I guess you missed the part where I mentioned the overworked employees being worked into a stupor...or didn't understand that it's because they have to work 2 or 3 full time jobs to afford both food and shelter that they are overworked zombies, unable to think well enough to stop the other higher ranking employees from instructing them to do stupid things. Increase the base pay so full time employees can afford food and shelter in the area they work in (or near) and you increase base competence because they no longer have to work 120 hour work weeks to survive.

AHHHH, but those at the top HAVE had their 'wages' go up far more than inflation, but not those at the bottom who would be making about $22 an hour if minimum wages were tied to inflation since their start.
A rising tide lifts all ships, OK, except for those already artificially 'lifted' WAY above the tide line. If all 'ships' floated on the tide, that saying would mean something. They don't.
OK, I'll go there, lets say everyone deserves to make >3 times what they used to make when the national minimum wage was started. That means a HUGE pay cut for those at the top, probably a 90%+ pay cut in most cases. Do that, and there's no problem at all affording the cost of paying the bottom 50% a living wage, which means anyone working full time is paid above the poverty line, no exceptions.
Yes, doing that will raise prices, which will require raising wages, which will raise prices...IF the top don't stop taking an obscenely unfair slice of the pie. If THEY pay themselves in the same manner they pay employees, there's no problem. They won't though.

That's obscene -- who rolls joints like that anymore?!

No, nothing about this was cool. It reproduced everything that was BAD about sci fi action movies.

The obscene amounts of light flicker, despite the fact that POWER SYSTEMS DO NOT WORK THAT WAY, would make JJ Abrams blush.

well that was pretty obnoxious. nothing like people running up to you on the street and yelling obscenities in your face

https://www.irishtimes.com/opinion/fintan-o-toole-obscene-salaries-encourage-contempt-for-the-simple-dignity-of-a-job-well-done-1.2449165

Ah, sweet childhood memories of flashlight lightsaber fights, Star Wars toys and Halloween costumes, now cut to you playing Battlefront and having some 13 year old brat screaming obscenities in your ear that would make a demon blanch.

Meh, that's debatable.

The women involved in the original scandal didn't claim to feel harassed.

She didn't even see the infamous picture.

In fact, she herself thought it was a obscene prank perpetrated by some conservatives who disapproved of her support for Weiner. (hehe)

Furthermore, the leakers weren't "whistleblowers" doing some ground-breaking investigative reporting on corrupt politicians.

They were right-wing lackeys who monitored Weiners communicates with the specific intent to dig up dirt.

From Wikipedia--

According to the New York Times, evidence later revealed that..


So..

Seems like Breitbart henchmen were hunting for some character-assassination dirt..

And Weiner accidentally handed it to them on a silver platter. (Hah)


There were supposedly 5 other women he sexted, and those scenarios may possibly constitute sexual harassment..

But, as far as the original scandal & dick-pic seen 'round the nation go..

A hilarious mistake lead to shaming and the end of a career.

Which sucks because Anthony Weiner was a fierce politician who was fighting the good fight.


So yeah, bad example for Oliver to pick.

Look up what the word bigot means. It describes nearly every talking point you've ever put forth here.

The only people who are truly threatened by gays are probably gay themselves, just in denial.

I'm not gay.

I even have a slight discomfort viewing gays kissing passionately. I also have a slight discomfort watching obscenely fat straight people kissing passionately. Or people who are vastly different ages kissing passionately. Or Republicans talking. Or responding to people who just say shit to cause a ruckus even though they really couldn't give a shit either way.

You're in there somewhere.

"Here are these incredibly creative people.
These are people that could change the world, and I go, why are you putting your energy into really gratuitous and obscene violence?"

Something about the human psyche that is really messed up - It could be the burst of adrenalin we get when we're grossed out.

But she is right, imagine what programmers could do if they put their minds to major issues. The problem is, can you make people watch? And, can they profit from it. That's the challenge.

Tags for this video have been changed from 'comic, offensive, obscene, sex, masturbation, amsterdam' to 'comic, offensive, obscene, sex, masturbation, amsterdam, Jim Jefferies' - edited by eric3579

You are absolutely right, the results of elections in Greece do not create an obligation for fiscal transfers from other European countries.

But that plays right into what Varoufakis has been saying for years, doesn't it? The program over the last seven years has reduced Greek output by a quarter, and thereby its ability to service and reduce its debt. The troika is offering more loans, loans that cannot be payed back, in return for a further reduction in Greece's ability to pay back those loans in the first place. Extend and pretend, all the way. Nevermind the humanitarian cost or the threat to democracy itself.

It is either counter-productive or aimed at a different goal entirely. Greece wants an end to those loans, and all the loss of sovereignty that comes with it, while the Eurogroup in particular wants to stick to a program that only increased Greece's dependency to a point where they can throw the entire country into unbearable misery at a moment's notice (e.g. cut ELA access).

Take the privatisation demands as an example. The program demands that Greece agrees to sell specific property at a specific price. Both parties are keenly aware that this price cannot be realised during a fire sale, yet they still demand a promise by the Greeks to do so. Any promise would be a lie and everyone knows it.

Same for the demanded specificity of Greece's plans. After decades of nepotism, a fresh government made up entirely of outsiders is supposed to draw up plans of more detail than any previous government came up with. And they cannot even rely on the bureaucracy, given that a great number of people in it are part of the nepotic system they are trying to undo in the first place.

Taxes, same thing. The first king of Greece (1832'ish) was a prince of Bavaria who was accompanied by his own staff of finance experts, and they failed miserably. Greece went through occupation, military junta and decades of nepotism, and the new government is supposed to fix that within months.

Those demands cannot be met. The Greeks know it, the troika knows it, the Eurogroup knows it.

Zizek called it the superego in his recent piece on Syriza/Greece:

"The ongoing EU pressure on Greece to implement austerity measures fits perfectly what psychoanalysis calls the superego. The superego is not an ethical agency proper, but a sadistic agent, which bombards the subject with impossible demands, obscenely enjoying the subject’s failure to comply with them. The paradox of the superego is that, as Freud saw clearly, the more we obey its demands, the more we feel guilty. Imagine a vicious teacher who assigns his pupils impossible tasks, and then sadistically jeers when he sees their anxiety and panic. This is what is so terribly wrong with the EU demands/commands: they do not even give Greece a chance – Greek failure is part of the game."

Aside from all that, the entire continent is in a recession. Not enough demand, not enough investment, unsustainable levels of unemployment. Greece was hit hardest, Greece was hit first. It's not the cause of the problem, it is the canary in the coal mine. And Italy is already looking very shaky...