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This man is POTUS

robdot says...

Trump (cont'd): "Then we got hit by the 'China' virus, and after the 'China' virus we did one of the best jobs in the world of doing everything including Operation Warp Speed and everything that that entailed. The therapeutics, the vaccines, everything we did and then they messed it up with the mandates, and they absolutely were killing our country with the mandates which should have never happened. It's just so sad to hear because this was all a self-inflicted wound from inflation to the loss of energy independence. And now add to that what's going on in Ukraine. That's genocide. What's happening in Ukraine, people have never seen anything like that before.

Please Clean Up Your Dog Poop

lucky760 says...

I don't have a lawn so I don't have this problem in front of my house, but I do encounter publicly available piles of dog excrement on sidewalks, in grass at the park, etc., and it always makes me livid at the many disgusting, nasty humans who don't seem to mind being so inconsiderate to their neighbors.

It was therapeutic watching this, despite that he did overdo it a little (hard to hold that against him though).

Hoof Restoration

http://www.usahealthcart.com/infinity-boost/ (Death Talk Post)

Mouse Cleans Up Garden Shed

How Not to Do Brownies

Buck says...

I ate a chocolate hash/pot ball at a party once and had a similar tripped out experience.

Another time I ate a cookie my sister was testing doses for cannabutter and it just knocked me out during a movie on the couch, woke up refreshed and hungry 4 hrs later. (I've also tried shrooms, ecstasy and acid at various times. )

Now I'm wondering if there was anything else in my choco ball of trippyness? Ah well, I just like a good bong now and again in my old age I guess. Though shrooms are by far the best high, best trip and long therapeutic effects afterwards. I might try that again. Good times!

newtboy said:

Rule 6: know what drug(s) you are taking.
I'm pretty certain this was not just marijuana. As a person who has ingested over an oz of AAA quality marijuana in a single sitting, I will confidently say there was something else in those brownies to have this effect....unless he has a mental disorder. This is not a normal reaction to excess thc. I expect he unintentionally just got wet (pcp).

Science to the rescue; this is how you rehab a broken back

newtboy says...

Thanks, that's nice of you to say.
Unfortunately, snorkeling up here means subjecting myself to hypothermia, so it probably won't happen much. There will be some while I set up my pond, but I doubt that will be as therapeutic as warm Hawaii waters. Maybe I should move!

SFOGuy said:

I am sorry to hear about your accident; I am glad you finally found a way on your own to "self-rehab" by snorkeling.
Swim on, my friend.

How to DMT

GenjiKilpatrick (Member Profile)

Your Brain On Shrooms

shagen454 says...

Thank goodness we have someone else here on the Sift (other than myself) that truly understands both the molecular structure AND the experience itself! I think "walls breathing" with a slight "therapeutic effect" would result in a Shulgin rating of 1 - where as the correct dosage with the right strain could very well end up with a Shulgin rating of 3 /5 potentially 4 - so the spectrum is vast. To reach those states on mushrooms I would say is potentially dangerous - due to duration and effects - if that is the state one wishes to see - I'd highly recommend smoking straight up very small doses of 5-MEO-DMT (which is potentially dangerous past say 7 milligrams so start small and actually weight the dose) or NN-DMT (up to 25 milligrams - which is not dangerous at all - one could smoke 200000000000000000000 mg and it's safe, "breakthrough" experience usually occurring somewhere in the 20mg-50mg range). I don't promote "breakthrough experiences" like the poet, mycologist & ethnobotanist + ultimate source of knowledge on the subject (Terence Mckenna) did - I think it's a lot crazier than any person can realize is possible but what I recommend is starting small and working up from there.

kir_mokum said:

yeah, you def. didn't do enough and/or the right strain.

Your Brain On Shrooms

BoneRemake says...

Oh that sucks.. I do them once a year at least for the therapeutic effect. It is never just things moving around and funny shades of light for me.

nanrod said:

All they've ever done for me is make the walls look like they're breathing and make the lighting brighten and dim spontaneously. so for me kind of a waste of time and they taste like shit.

Baffled by Stupidity: Richard Dawkins

shagen454 says...

See now I can tell you really know nothing about it, since you do not need to be a chemist. You could grab yopo seeds and just smoke those (they were found in a 3,000 year old bowl in Costa Rica - people have known about it for a long time, then for some reason it became a secret - I think Christianity stepped in to get rid of the knowledge of it), it's found throughout nature - you could grab some acacia bark, boil it and drink. It is safe and it is not dangerous. It's been studied many times and is still being studied for how it affects the brain & as well for it's natural therapeutic effects. It is believed to be endogenous - that is it already exists within your being (it's in many plants and animals, recently found produced in an animal's pineal gland). Not a huge Tool fan but they often allude to this substance, the pineal gland, Alex Grey's artwork - pretty sure they know full well of what it is.

Anyway, I totally did derail the comments and I do apologize for that, but you guys were calling me "religious" and downvoting me so I took offense. I derailed mostly to post the link about Dawkins having a profound experience that humbles his approach, it was a joke - but really I think all of us that have experienced the wonders would love people like Dawkins to spend the 5-10 minutes to experience it and then hear what he has to say about it.

*promote

newtboy said:

What @eric3579 said.
Not the first time you have hijacked a thread to espouse the wonders of DMT. Are you a chemist that makes the stuff or what? It is not a 'safe' drug in any way.
If it's not about being a 'religious experience', your interjection of it here is out of place and odd.

Brittany Maynard - Death with Dignity

Sniper007 says...

TONS of things cure cancer. All day, every day. Doctors have no clue what cancer is. All they can do is cut, burn, or poison and cross their fingers.

I didn't say Cannabis was THE cure. It is A cure used by thousands with amazing efficacy. Everyone is different.

Here's 60+ studies for your perusal if you insist on the superiority of western scientific research:

"Cannabis, and the cannabinoid compounds found within it, has been shown through a large cannabisplantamount of scientific, peer-reviewed research to be effective at treating a wide variety of cancers, ranging from brain cancer to colon cancer. Below is a list of over 60 studies that demonstrate the vast anti-cancer properties of cannabis.
Studies showing cannabis may combat brain cancer:
Cannabidiol (CBD) inhibits the proliferation and invasion in U87-MG and T98G glioma cells. Study published in the Public Library of Science journal in October 2013.
Tetrahydrocannabinol (THC) can kill cancer cells by causing them to self-digest. Study published in the Journal of Clinical Investigation in September 2013.
CBD is a novel therapeutic target against glioblastoma. Study published in Cancer Research in March 2013.
Local delivery of cannabinoid-filled microparticles inhibits tumor growth in a model of glioblastoma multiforme. Study published in Public Library of Science in January 2013.
Cannabinoid action inhibits the growth of malignant human glioma U87MG cells. Study published in Oncology Reports in July 2012.
Cannabidiol enhances the inhibitory effects of THC on human glioblastoma cell proliferation and survival. Study published in the Molecular Cancer Therapeutics journal in January 2010.
Cannabinoid action induces autophagy-mediated cell death in human glioma cells. Study published in The Journal of Clinical Investigation in May 2009.
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Study published in Cancer Research in March 2008.
Cannabinoids and gliomas. Study published in Molecular Neurobiology in June 2007.
Cannabinoids inhibit gliomagenesis. Study published in the Journal of Biological Chemistry in March 2007.
A pilot clinical study of THC in patients with recurrent glioblastoma multiforme. The results were published in the British Journal of Cancer in June 2006.
Cannabidiol inhibits human glioma cell migration through an independent cannabinoid receptor mechanism. Study published in the British Journal of Pharmacology in April 2005.
Cannabinoids inhibit the vascular endothelial growth factor pathway (VEGF) in gliomas. Study published in the Journal of Cancer Research in August 2004.
Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. Study published in the Journal of Pharmacology in November 2003.
Inhibition of glioma growth in vivo by selective activation of the CB2 cannabinoid receptor. Study published in the Journal of Cancer Research in August 2001.
Studies showing cannabis may combat colorectal cancer:
Cannabigerol (CBG) can inhibit colon cancer cells. Study published in the Oxford journal Carcinogenesis in October 2014.
Inhibition of colon carcinogenesis by a standardised Cannabis Sativa extract with high content of CBD. Study published in Phytomedecine in December 2013.
Chemopreventive effect of the non-psychotropic phytocannabinoid CBD on colon cancer. Study published in the Journal of Molecular Medecine in August 2012.
Cannabinoids against intestinal inflammation and cancer. Study published in Pharmacology Research in August 2009.
Action of cannabinoid receptors on colorectal tumor growth. Study published by the Cancer Center of the University of Texas in July 2008.
Studies showing cannabis may combat blood cancer:
The effects of cannabidiol and its synergism with bortezomib in multiple myeloma cell lines. Study published in the International Journal of Cancer in December 2013.
Enhancing the activity of CBD and other cannabinoids against leukaemia. Study published in Anticancer Research in October 2013.
Cannabis extract treatment for terminal acute lymphoblastic leukemia of Philadelphia chromosome (Ph1). Study published in Case Reports in Oncology in September 2013.
Expression of type 1 and type 2 cannabinoid receptors in lymphoma. Study published in the International Journal of Cancer in June 2008.
Cannabinoid action in mantle cell lymphoma. Study published in Molecular Pharmacology in November 2006.
THC-induced apoptosis in Jurkat leukemia. Study published in Molecular Cancer Research in August 2006.
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Study published in Blood American Society of Hemmatology in July 2002.
Studies showing cannabis can combat lung cancer:
Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of Icam-1. Study published in Biochemical Pharmacology in July 2014.
Cannabinoids inhibit angiogenic capacities of endothelial cells via release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells. Study published in Biochemical Pharmacology in June 2014.
COX-2 and PPAR-γ confer CBD-induced apoptosis of human lung cancer cells. Study published in Molecular Cancer Therapeutics in January 2013.
CBD inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. Study published in the Journal of the Federation of American Societies for Experimental Biology in April 2012.
Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non–small cell lung cancer growth and metastasis. Study published in Cancer Prevention Research in January 2011.
THC inhibits epithelial growth factor-induced (EGF) lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Study published in the journal Oncogene in July 2007.
Studies showing cannabis may combat stomach cancer:
Cannabinoid receptor agonist as an alternative drug in 5-Fluorouracil-resistant gastric cancer cells. Study published in Anticancer Research in June 2013.
Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. Study published in the Journal of Cellular Biochemistry in March 2011.
Studies showing cannabis may combat prostrate cancer:
Cannabinoids can treat prostate cancer. Study published by the National Institute of Health in October 2013.
Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms. Study published in the British Journal of Pharmacology in December 2012.
The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications. Study published in the Indian Journal of Urology in January 2012.
Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. Study published in Anticancer Research in November 2011.
Studies showing cannabis may combat liver cancer:
Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma (CHC). Study published in Cell Death and Disease in May 2013.
Evaluation of anti-invasion effect of cannabinoids on human hepatocarcinoma cells. Study published on the site Informa Healthcare in February 2013.
Antitumoral action of cannabinoids on hepatocellular carcinoma. Study published in Cell Death and Differentiation in April 2011.
Studies showing cannabis may combat pancreatic cancer:
Cannabinoids inhibit energetic metabolism and induce autophagy in pancreatic cancer cells. Study published in Cell Death and Disease in June 2013.
Cannabinoids Induce apoptosis of pancreatic tumor cells. Study published in Cancer Research in July 2006.
Studies showing cannabis may combat skin cancer:
Cannabinoid receptor activiation can combat skin cancer. Study published by the National Institute of Health in October 2013.
Cannabinoids were found to reduce skin cancer by 90% in just 2 weeks. Study published in the Journal of Pharmacy and Pharmacology in July 2013.
Cannabinoid receptors as novel targets for the treatment of melanoma. Study published in the Journal of the Federation of American Societies for Experimental Biology in December 2006.
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. Study published in the Journal of Clinical Investigation, in January 2003.
Studies showing cannabis may combat other types of cancer:
Bladder: Marijuana reduces the risk of bladder cancer. Study published in the Medscape site in May 2013.
Kaposi sarcoma: Cannabidiol inhibits growth and induces programmed cell death in Kaposi sarcoma–associated herpesvirus-infected endothelium. Study published in the journal Genes & Cancer in July 2012.
Nose, mouth, throat, ear: Cannabinoids like THC inhibit cellular respiration of human oral cancer cells. Study by the Department of Pediatrics at the State University of New York, published in June 2010.
Bile duct: The dual effects of THC on cholangiocarcinoma cells: anti-invasion activity at low concentration and apoptosis induction at high concentration. Study published in Cancer Investigation in May 2010.
Ovaries: Cannabinoid receptors as a target for therapy of ovarian cancer. Study published on the American Association for Cancer Research website in 2006.
Preparation and characterisation of biodegradable microparticles filled with THC and their antitumor efficacy on cancer cell lines. Study published in the Journal of Drug Targeting in September 2013.
CBD Cannabidiol as a potential anticancer drug. Study published in the British Journal of Pharmacology in February 2013.
Cannabinoids as anticancer modulators. Study published in the Progress in Lipid Research journal in January 2013.
CBD inhibits angiogenesis by multiple mechanisms. Study published in the British Journal of Pharmacology in November 2012.
Towards the use of cannabinoids as antitumour agents. Study published in Nature in June 2012.
Cannabinoid-associated cell death mechanisms in tumor models. Study published in the International Journal of Oncology in May 2012.
Cannabinoids, endocannabinoids and cancer. Study published in Cancer Metastasis Reviews in December 2011.
The endocannabinoid system and cancer: therapeutic implication. Study published in the British Journal of Pharmacology in July 2011.
This list was compiled in part by Alchimiaweb.com.
– TheJointBlog"

ChaosEngine said:

No, you'd be remiss if you opined blatant misinformation.

While there is a possibility that cannabinoids can inhibit tumour growth, there is nothing even close to a solid evidence base to show that "cannabis cures cancer".

RIP-Robin Williams :(

Trancecoach says...

The link selected was for its clarity of description, not for its modus operandi, but, if you like, here's additional support for the non-dichotomous (not "black and white") assertion I've made (despite your suggestions to the contrary).

Simply put, suicidality is a side-effect of anti-depressants due, in part, to the increased energy or motivation that could arise as a result of the commencement of a round of SSRIs. Someone suffering from a severe depressive episode may, within a few weeks of commencing an SSRI, avail themselves to the means for suicide (in the absence of therapeutic interventions) which, in the weeks previous, might have seemed too difficult or like too much work to pull off.

As a psychologist and clinician myself, I am trained to work closely with individuals struggling with depressive episodes with an eye on this very issue. Sadly, for whatever reason, Robin's therapist(s) were unable to intervene as quickly as was necessary, speculating as I have, that a recent round with anti-depressants was at play.

eric3579 (Member Profile)

radx says...

Always am.

And I already had a sore throat from yelling at my screen when I read the parts about expanding patents on "diagnostic, therapeutic, and surgical methods for the treatment of humans or animals".

Then I saw this picture of our beloved Dave who rose from his golden throne to declare to the peasants that austerity will be made permanent, since it's such a wonderful sight to see hundreds of thousands of people at food banks.

What a day...

eric3579 said:

Wikileaks TPP agreement leaked. Thought you might be interested.
http://wikileaks.org/tpp/



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