You should check out his other songs. Most i'm guessing you will know. They are all amazingly well done. I'm surprised more people don't love his stuff. Here are my faves.
*related https://videosift.com/video/CRISPR-Cas9-Mr-Sandman-Parody-A-Capella-Science
*related https://videosift.com/video/A-Capella-Science-Bohemian-Gravity
*related https://videosift.com/video/Gravitational-Waves-Jam
*related https://videosift.com/video/PLUTO-MARS-Outbound-Probe-A-Capella-Science

CRISPR-Cas9 ("Mr. Sandman" Parody) | A Capella Science has been added as a related post - related requested by eric3579.

A Capella Science - Bohemian Gravity! has been added as a related post - related requested by eric3579.

Gravitational Waves Jam has been added as a related post - related requested by eric3579.

PLUTO MARS - Outbound Probe (A Capella Science) has been added as a related post - related requested by eric3579.

My long time issue with the "they would be too intelligent/evolved to have any interest in us" type scenario, such as he puts as number two here, is that we go through great lengths to try and research and understand very primitive life. There are efforts being made to talk to dolphins and apes. We're looking to build ships to crash or land ships onto Titan to see if there is microbial life on a moon orbiting a gas giant, not to mention work to see if Mars once upon had life. So the very fact we're able to get off our little rock (though not much off it), I think would warrant a stop and look, perhaps to help answer what was life like at such an early stage of evolution.

Not said stop and look doesn't imply any sort of communications. Indeed there may be a Prime Directive like thing with them where by they see and observe, but leave no evidence of such a visit (alien abductions being just mental illness coupled with abuse or other issues).

Now distance is a super valid point, but by far the most likely point is the survivability window, which he talks about in point three. We're still a level zero civilization (Kardashev scale) and decades until we reach a level one civilization (unfortunately it seems delayed even further due to some very anti-science moves being made by certain groups). Moving up that scale is only one thing, avoiding killing ourselves via war is another huge one. With CRISPR technology advancing, there is a very real danger of a Division/Stand/Utopia type disease coming to the foreground, especially if driven by a zealot (ala Division and Utopia). I highly doubt a man made black hole or something, but war or a CRISPR engineered disease... Not to mention the natural disasters he mentioned, and others, such as huge gamma ray bursts and others that we've managed to avoid. And we'd have to think that most civilizations go through somewhat similar phases, with a universe that is fairly hostile to life, even if many planets are capable of at least starting life. Generally I figure that most civilizations never make it past the stage we are at now, and those that do probably don't get to stage two and beyond (to be fair, I doubt any civilization can achieve stage two on Kardashev's scale as it goes beyond knowledge needed, but materials and more).

Back to the technology of communications point. I've generally figured if you are space faring, you gave up on radio communications and are using strange properties or something along those lines.

CRISPR-Cas9
Bring me a gene
Encoding for a specific protein
Make a few snips at this coded locus
You work so well inside a streptococcus
Cas9
I'm so alone
Without your scissors in my chromosome
Cut me up and do it clean
CRISPR-Cas9 bring me a gene

CRISPR-Cas9
Keep me a gene
A viral sequence you've already seen
Chopped into bits and stored as genomic
With clustered repeats
That are palindromic
Cas9
Bind with this code
Use it to target infections of old
Immunized like a vaccine
CRISPR-Cas9 keep me a gene

CRISPR-Cas9
Cut me a gene
With a precision that I've never seen
Unzip a strand and interrogate it
Seek out your sequence until you locate it
Cas9
Lock into place
And do your job as endonuclease
Chop just like a guillotine
CRISPR-Cas9 cut me a gene

Snip snap!
CRISPR-Cas9
CRISPR-Cas9

CRISPR-Cas9
Bring me a gene
By commandeering my repair routine
A strand to match your severed location
For some homologous recombination
Cas9
Cheap and precise
Rewriting genomes from microbes to mice
And soon the humble human being
CRISPR-Cas9 bring me a gene

CRISPR-Cas9
Give us a gene
Give us a miracle like that one Nazarene
‘Cause giving the lame their legs and the blind their sight is
In view for dystrophy and retinitis
But CRISPR-Cas9
What if you fall
Outside our power and inside us all
That really could incite a scene

When this terrible wonderful power unsettling
Opens the door to unethically meddle
Is ev’ry congenital malady bettered
Sufficient to warrant genetics unfettered
To modify man in the manner of Gattaca
Raise up a mammoth or make a rattata
Dramatical medical means to eradicate aging
Or cancer or make a fanatic
A mass epidemic a weapon nefarious
Single mosquito to wipe out malaria
Send in a viral infection to ferry a
Cure to the cells of an HIV carrier
Freed of disease as we're free to uncover
What nature and accident failed to discover
And free to be other than
All that we ever have been

CRISPR-Cas9
CRISPR-Cas9

Oh CRISPR-Cas9
Bring us a gene
You wondrous ribonucleoprotein
You have the power to vanquish or save us
Who would have thought that the microbe that gave us
Cas9
S. pyogenes
The source of strep and flesh-eating disease
Housed this marvellous machine
Full of uses great and obscene
CRISPR-Cas9 bring us
Please don't sting us
Cas9 bring us a gene

With adenine
And thiamine
Incite a scene
Cas9 bring us a gene!

CRISPR: A Gene-Editing Superpower has been added as a related post - related requested by Mordhaus on that post.

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Kurzgesagt on CRISPR

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