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We all have that friend online...

Why American and European Trucks Are So Different

luxintenebris says...

as long as the driver has a large-mouth bottle, all american trucks have toilets.*

did read that there was a correlation between bladder cancer & truck drivers. was surmised, that holding your toilet had a part in the troubles. maybe, will have a definitive answer when amazon workers start having the same issues.

also many uti's.

read this reading up on school bathroom policies. a lot of uti's & colon-related problems - kids' tracts lose the ability to feel the urge & end up w/constipation and incontinent issues - in schools w/"hold it or lose recess" rules. (special place in hell, or the backyard, for those enforcers) - so the theory might hold water.

(a long drive for o̶n̶e̶ two puns.)



* "Most of us do carry pee bottles. But you have to stop to utilize them. I don't have enough hands to steer, shift, hold the bottle & direct Little Richard in the right direction all at the same time. Stopping to water the flowers is no longer an option, as it could lead to a sex criminal(sic) charge for indecent exposure."

Red Bull Valparaiso Cerro Abajo 2019

'Was that disruptive?': congressman "blasts" Trump official

newtboy says...

What he neglected to say, and would be important, is at 25% higher it is loud enough to cause permanent deafness, <50% higher, around 180, that's loud enough to kill a human. I wish he had asked the witness if he would sit for double the original volume, would that be disruptive? Now ask Trump.
16000 times louder....16000 times, when 2 times louder is well beyond the level that is deadly. Let that sink in. 8000 times louder than deadly. That's not only deafening for hundreds or thousands of miles in every direction (sound travels farther with less loss under water), it's undeniably deadly for miles....every time they ping it....to nearly everything. That level of sonic energy can shatter stone, what would one expect it to do to a tissue paper thin swim bladder?

I am astonished they're still trying this tech after the outrage at the hundreds or thousands of dolphins and whales it killed early on, years ago.

Why I Left the Left

enoch says...

the left won the moral argument decades ago,now a small cadre a shrieking harpies has taken over to....ok..i don't know WHAT they are trying to do,because everytime i try to speak to one of those snowflakes,they spray me with pepper spray,call me a rapist and run to their safe space.

or they tell me that i am not entitled to an opinion,because i am a hetero-white-male.

not saying a discussion with someone on the ultra right fares any better.either they want to share their adoration of their corporate jesus..joel olsteen..or they are constantly trying to berate me with neo-fascist literature,and show me just how patriotic a super patriot like them REALLY is,and then tell me why they couldn't join the military due to horrible bunions.

and of course one mention of muslims and they wet themselves.getting sick of loaning out my extra clothes because their bladder gets weak at the mere mention of brown people.

for years we have watched the left lose their way,and get lost in an ocean of rhetoric and faux outrage,and the same has happened with the right.

the extremes have taken hold of the megaphone,and are trying to shout each other down with their own sanctimonious self-righteous moralizing.

so the left is in the corner picking boogers and the right has gone fucking insane.

i'm telling you guys...
trump is not the disease...
he is a symptom.

our country is very very sick right now.

and i fear it is only going to get worse.

i predicted when trump won that he would rival bush in his ineptness and bungling buffoonery.well here it is a month into his presidency and i think i can say with some conviction:i was wrong..it is going to be so much worse than bush.

i need a drink...

Building a Fish Tower in a pond

Zawash says...

Lower water pressure would inflate the swim bladder, increasing the buoyancy. Higher pressure makes the bladder easier to empty, making it easier to sink.
You get this effect when scuba diving - it is harder to get down from the surface than to get deeper when you're already several feet below.

Payback said:

Lower water pressure means they would sink easier, not float.

Building a Fish Tower in a pond

AeroMechanical says...

That's an interesting question, but I figure the water pressure in the box can't be different than the pressure difference you'd get from the equivalent change of depth, which can't be very much. Surely their bladders allow them to swim up or down a few feet. I doubt they're stuck in any way. Maybe they congregate there because the water in the box is warmer or because there is more light. Maybe they just find it interesting. I guess I shouldn't feel bad about fish in an aquarium since they seem to enjoy the experience.

Spacedog79 said:

The question I always have when I see these is do the fish really like it, or does the change in pressure on the water under vacuum affect their swim bladders so they get too buoyant and get a bit stuck inside it?

Building a Fish Tower in a pond

Spacedog79 says...

The question I always have when I see these is do the fish really like it, or does the change in pressure on the water under vacuum affect their swim bladders so they get too buoyant and get a bit stuck inside it?

Could we, should we annihilate Zika mosquitoes?

newtboy says...

Whenever there's a mosquito vectored disease, people talk about eradicating mosquitos, but never consider their role in the food chain, and it is not a small role.
They also never consider the effects of the eradication methods, which are often poison sprayed into the air or onto ponds. Decades ago, a 12 year old boy designed and made a device for eradicating mosquitos in water using sound waves for a science project, and it worked. He tuned his device to resonate at the same frequency as the gas bladder in mosquito larva, popping it and killing the mosquitos without effecting anything else, and leaving no residue. For some reason, I never hear about that method being used, but instead often see people dosing small ponds with poison, oil, or bacteria, all of which harm other organisms.
Targeting single strains of mosquito with genetics may be a good way to deal with disease issues, but will certainly also have unexpected unpredictable consequences. I hope they remember the fiasco caused by creating killer bees and study the issue from all sides thoroughly before releasing them into the wild.

newtboy (Member Profile)

Biggest Bladder Stone Ever! GRAPHIC! Saved By Youtube!

worthwords says...

with a stone that size you won't be thinking of passing - the urine would drain around it and if it obstructed then your kidneys would eventually fail.
You might be interested in stag horn calculi in humans - usually precipitated by proteus infection - these clog up the calyces in a branching fashion which would be impossible to pass.

The largest stone recorded in a human is believed to be this one at over 800grams.

http://www.mirror.co.uk/news/weird-news/bladder-stone-kilo-amazing-pictures-2990838

Biggest Bladder Stone Ever! GRAPHIC! Saved By Youtube!

newtboy says...

OMG!!!! Think about that if she was human sized, 10 times the size it is! It would be like having a large bowling ball in your bladder! Now consider trying to PASS that stone....I just passed out thinking about it.
I'm astonished this dog survived to get the surgery...and quite pleased as well.
I'm awestruck at this video, and also pleasantly surprised Youtube watchers paid for the entire surgery...good on ya, people.

Yeonmi Park - North Korea's Black Market Generation

newtboy says...

Those draconian bastards, the damn government, keeping me from my business of selling endangered tiger gall bladders. Regulations are all evil, they must be, Little Kim and Hitler used regulations, so...evil. We must be free to do whatever we want because we all know that any regulations are the same thing as draconian totalitarian dictatorship.

Strap and Crap

Brittany Maynard - Death with Dignity

Sniper007 says...

TONS of things cure cancer. All day, every day. Doctors have no clue what cancer is. All they can do is cut, burn, or poison and cross their fingers.

I didn't say Cannabis was THE cure. It is A cure used by thousands with amazing efficacy. Everyone is different.

Here's 60+ studies for your perusal if you insist on the superiority of western scientific research:

"Cannabis, and the cannabinoid compounds found within it, has been shown through a large cannabisplantamount of scientific, peer-reviewed research to be effective at treating a wide variety of cancers, ranging from brain cancer to colon cancer. Below is a list of over 60 studies that demonstrate the vast anti-cancer properties of cannabis.
Studies showing cannabis may combat brain cancer:
Cannabidiol (CBD) inhibits the proliferation and invasion in U87-MG and T98G glioma cells. Study published in the Public Library of Science journal in October 2013.
Tetrahydrocannabinol (THC) can kill cancer cells by causing them to self-digest. Study published in the Journal of Clinical Investigation in September 2013.
CBD is a novel therapeutic target against glioblastoma. Study published in Cancer Research in March 2013.
Local delivery of cannabinoid-filled microparticles inhibits tumor growth in a model of glioblastoma multiforme. Study published in Public Library of Science in January 2013.
Cannabinoid action inhibits the growth of malignant human glioma U87MG cells. Study published in Oncology Reports in July 2012.
Cannabidiol enhances the inhibitory effects of THC on human glioblastoma cell proliferation and survival. Study published in the Molecular Cancer Therapeutics journal in January 2010.
Cannabinoid action induces autophagy-mediated cell death in human glioma cells. Study published in The Journal of Clinical Investigation in May 2009.
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Study published in Cancer Research in March 2008.
Cannabinoids and gliomas. Study published in Molecular Neurobiology in June 2007.
Cannabinoids inhibit gliomagenesis. Study published in the Journal of Biological Chemistry in March 2007.
A pilot clinical study of THC in patients with recurrent glioblastoma multiforme. The results were published in the British Journal of Cancer in June 2006.
Cannabidiol inhibits human glioma cell migration through an independent cannabinoid receptor mechanism. Study published in the British Journal of Pharmacology in April 2005.
Cannabinoids inhibit the vascular endothelial growth factor pathway (VEGF) in gliomas. Study published in the Journal of Cancer Research in August 2004.
Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. Study published in the Journal of Pharmacology in November 2003.
Inhibition of glioma growth in vivo by selective activation of the CB2 cannabinoid receptor. Study published in the Journal of Cancer Research in August 2001.
Studies showing cannabis may combat colorectal cancer:
Cannabigerol (CBG) can inhibit colon cancer cells. Study published in the Oxford journal Carcinogenesis in October 2014.
Inhibition of colon carcinogenesis by a standardised Cannabis Sativa extract with high content of CBD. Study published in Phytomedecine in December 2013.
Chemopreventive effect of the non-psychotropic phytocannabinoid CBD on colon cancer. Study published in the Journal of Molecular Medecine in August 2012.
Cannabinoids against intestinal inflammation and cancer. Study published in Pharmacology Research in August 2009.
Action of cannabinoid receptors on colorectal tumor growth. Study published by the Cancer Center of the University of Texas in July 2008.
Studies showing cannabis may combat blood cancer:
The effects of cannabidiol and its synergism with bortezomib in multiple myeloma cell lines. Study published in the International Journal of Cancer in December 2013.
Enhancing the activity of CBD and other cannabinoids against leukaemia. Study published in Anticancer Research in October 2013.
Cannabis extract treatment for terminal acute lymphoblastic leukemia of Philadelphia chromosome (Ph1). Study published in Case Reports in Oncology in September 2013.
Expression of type 1 and type 2 cannabinoid receptors in lymphoma. Study published in the International Journal of Cancer in June 2008.
Cannabinoid action in mantle cell lymphoma. Study published in Molecular Pharmacology in November 2006.
THC-induced apoptosis in Jurkat leukemia. Study published in Molecular Cancer Research in August 2006.
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Study published in Blood American Society of Hemmatology in July 2002.
Studies showing cannabis can combat lung cancer:
Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of Icam-1. Study published in Biochemical Pharmacology in July 2014.
Cannabinoids inhibit angiogenic capacities of endothelial cells via release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells. Study published in Biochemical Pharmacology in June 2014.
COX-2 and PPAR-γ confer CBD-induced apoptosis of human lung cancer cells. Study published in Molecular Cancer Therapeutics in January 2013.
CBD inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. Study published in the Journal of the Federation of American Societies for Experimental Biology in April 2012.
Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non–small cell lung cancer growth and metastasis. Study published in Cancer Prevention Research in January 2011.
THC inhibits epithelial growth factor-induced (EGF) lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Study published in the journal Oncogene in July 2007.
Studies showing cannabis may combat stomach cancer:
Cannabinoid receptor agonist as an alternative drug in 5-Fluorouracil-resistant gastric cancer cells. Study published in Anticancer Research in June 2013.
Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. Study published in the Journal of Cellular Biochemistry in March 2011.
Studies showing cannabis may combat prostrate cancer:
Cannabinoids can treat prostate cancer. Study published by the National Institute of Health in October 2013.
Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms. Study published in the British Journal of Pharmacology in December 2012.
The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications. Study published in the Indian Journal of Urology in January 2012.
Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. Study published in Anticancer Research in November 2011.
Studies showing cannabis may combat liver cancer:
Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma (CHC). Study published in Cell Death and Disease in May 2013.
Evaluation of anti-invasion effect of cannabinoids on human hepatocarcinoma cells. Study published on the site Informa Healthcare in February 2013.
Antitumoral action of cannabinoids on hepatocellular carcinoma. Study published in Cell Death and Differentiation in April 2011.
Studies showing cannabis may combat pancreatic cancer:
Cannabinoids inhibit energetic metabolism and induce autophagy in pancreatic cancer cells. Study published in Cell Death and Disease in June 2013.
Cannabinoids Induce apoptosis of pancreatic tumor cells. Study published in Cancer Research in July 2006.
Studies showing cannabis may combat skin cancer:
Cannabinoid receptor activiation can combat skin cancer. Study published by the National Institute of Health in October 2013.
Cannabinoids were found to reduce skin cancer by 90% in just 2 weeks. Study published in the Journal of Pharmacy and Pharmacology in July 2013.
Cannabinoid receptors as novel targets for the treatment of melanoma. Study published in the Journal of the Federation of American Societies for Experimental Biology in December 2006.
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. Study published in the Journal of Clinical Investigation, in January 2003.
Studies showing cannabis may combat other types of cancer:
Bladder: Marijuana reduces the risk of bladder cancer. Study published in the Medscape site in May 2013.
Kaposi sarcoma: Cannabidiol inhibits growth and induces programmed cell death in Kaposi sarcoma–associated herpesvirus-infected endothelium. Study published in the journal Genes & Cancer in July 2012.
Nose, mouth, throat, ear: Cannabinoids like THC inhibit cellular respiration of human oral cancer cells. Study by the Department of Pediatrics at the State University of New York, published in June 2010.
Bile duct: The dual effects of THC on cholangiocarcinoma cells: anti-invasion activity at low concentration and apoptosis induction at high concentration. Study published in Cancer Investigation in May 2010.
Ovaries: Cannabinoid receptors as a target for therapy of ovarian cancer. Study published on the American Association for Cancer Research website in 2006.
Preparation and characterisation of biodegradable microparticles filled with THC and their antitumor efficacy on cancer cell lines. Study published in the Journal of Drug Targeting in September 2013.
CBD Cannabidiol as a potential anticancer drug. Study published in the British Journal of Pharmacology in February 2013.
Cannabinoids as anticancer modulators. Study published in the Progress in Lipid Research journal in January 2013.
CBD inhibits angiogenesis by multiple mechanisms. Study published in the British Journal of Pharmacology in November 2012.
Towards the use of cannabinoids as antitumour agents. Study published in Nature in June 2012.
Cannabinoid-associated cell death mechanisms in tumor models. Study published in the International Journal of Oncology in May 2012.
Cannabinoids, endocannabinoids and cancer. Study published in Cancer Metastasis Reviews in December 2011.
The endocannabinoid system and cancer: therapeutic implication. Study published in the British Journal of Pharmacology in July 2011.
This list was compiled in part by Alchimiaweb.com.
– TheJointBlog"

ChaosEngine said:

No, you'd be remiss if you opined blatant misinformation.

While there is a possibility that cannabinoids can inhibit tumour growth, there is nothing even close to a solid evidence base to show that "cannabis cures cancer".



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