Scientists regenerate hair on bald mouse

Above, your moment of science zen for the weekend. Using an innovative application of stem cells, researchers at the Tokyo University of Science have regenerated hair on a bald mouse.

Their accomplishment is described as a breakthrough, and inspires hopes of an alternative to hair transplants for bald guys who rely on toupees and comb-overs (or as they're known in Japan, "bar codes").

From a blog post at the Wall Street Journal, by Eleanor Warnock:

After cultivating two different kinds of cells taken from hair follicles in mice, the team transplanted the cells into the hair follicles of a bald mouse. Within three weeks, 74% of the hair follicles implanted with the cells grew back hair. The new hair connected with nerves and surrounding tissues showing that the follicles had become fully functional and were able to regrow hair even after hair was pulled out. The scientists were also able to play around with the density and color of the hair by changing the type of cells they transplanted into the mouse’s hair follicles. When they used cells from a human hair follicle, a human hair grew.

The results were published this week in the online journal Nature Communications. Jokes aside, the focus isn't so much male premature baldness, but helping people who have lost hair due to injury or disease. Not because premature baldness isn't a problem worth addressing, but because the technique at work here would be tough to apply for larger areas of hair growth. (thanks, @steppinlazer)

- from BoingBoing

>> ^Sarzy:

As someone whose genes pretty much guarantee I will eventually start balding, this intrigues me.

This technique doesn't sound very useful for you due not only to the difficulties they mention, but also because it wouldn't fix the underlying problem, which is that chemical signalling in your scalp is telling your hair cells to atrophy. What you'll probably need to do is wait for a drug that inhibits your natural levels of hormones such as Prostaglandin D2 (or it's receptor) in the scalp. This hormone (and a derivitive) seems to be the one that lead to baldness, so hopefully help is around the corner.

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